Evidence map›Paper›PMID 24473958›Full record

Trial reportRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2013

Lack of difference between continuous versus intermittent heparin infusion on maintenance of intra-arterial catheter in postoperative pediatric surgery: a randomized controlled study.

Maria Carolina Witkowski, Maria Antonieta P de Moraes, Cora Maria F Firpo

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01097031 (Continuous or Intermittent for Keeping Arterial Catheter in Children), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01097031 completednot on this map

Continuous or Intermittent for Keeping Arterial Catheter in Children: A Randomized Clinical Trial

TypeobservationalSponsorInstituto de Cardiologia do Rio Grande do SulRan2007 to 2009Enrolled140ConditionsBlood PressureArmsInfusion Intermittent
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria Carolina WitkowskiHospital de Clínicas de Porto Alegre, Porto AlegreRS, Brasil.
Maria Antonieta P de MoraesFundação Universitária de Cardiologia, Porto AlegreRS, Brasil.
Cora Maria F FirpoFundação Universitária de Cardiologia, Porto AlegreRS, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare two systems of arterial catheters maintenance in postoperative pediatric surgery using intermittent or continuous infusion of heparin solution and to analyze adverse events related to the site of catheter insertion and the volume of infused heparin solution.

methodsRandomized control trial with 140 patients selected for continuous infusion group (CIG) and intermittent infusion group (IIG). The variables analyzed were: type of heart disease, permanence time and size of the catheter, insertion site, technique used, volume of heparin solution and adverse events. The descriptive variables were analyzed by Student's t-test and the categorical variables, by chi-square test, being significant p<0.05.

resultsThe median age was 11 (0-22) months, and 77 (55%) were females. No significant differences between studied variables were found, except for the volume used in CIG (12.0±1.2mL/24 hours) when compared to IIG (5.3±3.5mL/24 hours) with p<0.0003.

conclusionsThe continuous infusion system and the intermittent infusion of heparin solution can be used for intra-arterial catheters maintenance in postoperative pediatric surgery, regardless of patient's clinical and demographic characteristics. Adverse events up to the third postoperative day occurred similarly in both groups. However, the intermittent infusion system usage in underweight children should be considered, due to the lower volume of infused heparin solution [ClinicalTrials.gov Identifier: NCT01097031].

Indexed as

Catheterization, PeripheralAnticoagulantsCatheters, IndwellingFemaleHeparinHumansInfantInfant, NewbornInfusions, Intra-ArterialMalePostoperative PeriodAnticoagulantsHeparin

Identifiers

PMID24473958
PMCPMC4183044

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.