Evidence map›Paper›PMID 24473459›Full record

Trial reportEuropean journal of clinical nutrition2014

Long-term effects of a Palaeolithic-type diet in obese postmenopausal women: a 2-year randomized trial.

C Mellberg, S Sandberg, M Ryberg, M Eriksson, S Brage, C Larsson, T Olsson, B Lindahl

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 14 syntheses or guidelines pooled it.

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  6. Reduction in saturated fat intake for cardiovascular disease.The Cochrane database of systematic reviews · 2020
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  7. Reduction in saturated fat intake for cardiovascular disease.The Cochrane database of systematic reviews · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

C MellbergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
S SandbergDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå University, Umeå, Sweden.
M RybergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
M ErikssonDepartment of Statistics, USBE, Umeå University, Umeå, Sweden.
S BrageMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
C Larsson1] Department of Food and Nutrition, and Sport Science, University of Gothenburg, Gothenburg, Sweden [2] Department of Food and Nutrition, Umeå University, Umeå, Sweden.
T OlssonDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
B LindahlDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå University, Umeå, Sweden.

Funding

Medical Research Council MC_U106179473Medical Research Council MC_UU_12015/3
6 · The paper itself

Abstract

BACKGROUND/

objectivesShort-term studies have suggested beneficial effects of a Palaeolithic-type diet (PD) on body weight and metabolic balance. We now report the long-term effects of a PD on anthropometric measurements and metabolic balance in obese postmenopausal women, in comparison with a diet according to the Nordic Nutrition Recommendations (NNR). SUBJECTS/

methodsSeventy obese postmenopausal women (mean age 60 years, body mass index 33 kg/m(2)) were assigned to an ad libitum PD or NNR diet in a 2-year randomized controlled trial. The primary outcome was change in fat mass as measured by dual-energy X-ray absorptiometry.

resultsBoth groups significantly decreased total fat mass at 6 months (-6.5 and-2.6 kg) and 24 months (-4.6 and-2.9 kg), with a more pronounced fat loss in the PD group at 6 months (P<0.001) but not at 24 months (P=0.095). Waist circumference and sagittal diameter also decreased in both the groups, with a more pronounced decrease in the PD group at 6 months (-11.1 vs-5.8 cm, P=0.001 and-3.7 vs-2.0 cm, P<0.001, respectively). Triglyceride levels decreased significantly more at 6 and 24 months in the PD group than in the NNR group (P<0.001 and P=0.004). Nitrogen excretion did not differ between the groups.

conclusionsA PD has greater beneficial effects vs an NNR diet regarding fat mass, abdominal obesity and triglyceride levels in obese postmenopausal women; effects not sustained for anthropometric measurements at 24 months. Adherence to protein intake was poor in the PD group. The long-term consequences of these changes remain to be studied.

Indexed as

DietAbsorptiometry, PhotonAgedBlood GlucoseBody Mass IndexBody WeightCholesterol, HDLCholesterol, LDLDietary ProteinsEnergy IntakeEnergy MetabolismFemaleHumansInsulinMiddle AgedNutrition AssessmentBlood GlucoseCholesterol, HDLCholesterol, LDLDietary ProteinsInsulinTriglycerides

Identifiers

PMID24473459
PMCPMC4216932

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.