ArticleScientific reports2014
Genomic analysis of thermophilic Bacillus coagulans strains: efficient producers for platform bio-chemicals.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- 4,6-α-Glucanotransferase: An enzymatic biocatalyst for the modification of starch and starch-food systems.Food chemistry: X · 2026Review
- Probiotic Potential ofFoods (Basel, Switzerland) · 2026Article
- Engineered microbial platform confers resistance against heavy metals via phosphomelanin biosynthesis.Nature communications · 2025Article
- Expanded genome and proteome reallocation in a novel, robustmSystems · 2024Article
- Harnessing the dual nature of Bacillus (Weizmannia) coagulans for sustainable production of biomaterials and development of functional food.Microbial biotechnology · 2024Review
- Progress of research and application ofFrontiers in cellular and infection microbiology · 2024Review
- CRISPR-Cas-Based Engineering of Probiotics.Biodesign research · 2023Review
- Metabolic engineering for the production of acetoin and 2,3-butanediol at elevated temperature inFrontiers in bioengineering and biotechnology · 2023Article
- In vitro assessment of probiotic attributes for strains contained in commercial formulations.Scientific reports · 2022Article
- A Comparative Analysis ofInternational journal of molecular sciences · 2022Article
- Complete genome sequence ofJournal of animal science and technology · 2021Article
- Biorefinery Concept EmployingMicroorganisms · 2021Article
- Prebiotic properties of Bacillus coagulans MA-13: production of galactoside hydrolyzing enzymes and characterization of the transglycosylation properties of a GH42 β-galactosidase.Microbial cell factories · 2021Article
- A cold shock protein promotes high-temperature microbial growth through binding to diverse RNA species.Cell discovery · 2021Article
- Batch and Continuous Lactic Acid Fermentation Based on A Multi-Substrate Approach.Microorganisms · 2020Article
- Complete Genome Sequence of Lactobacillus oris J-1, a Potential Probiotic Isolated from the Human Oral Microbiome.Genome announcements · 2016Article
- Complete genome sequence of thermophilic Bacillus smithii type strain DSM 4216(T).Standards in genomic sciences · 2016Article
- Systematic unravelling of the biosynthesis of poly (L-diaminopropionic acid) in Streptomyces albulus PD-1.Scientific reports · 2015Article
- Draft Genome Sequence of Bacillus coagulans NL01, a Wonderful l-Lactic Acid Producer.Genome announcements · 2015Article
- Genomic analysis of a ginger pathogen Bacillus pumilus providing the understanding to the pathogenesis and the novel control strategy.Scientific reports · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbial strains with high substrate efficiency and excellent environmental tolerance are urgently needed for the production of platform bio-chemicals. Bacillus coagulans has these merits; however, little genetic information is available about this species. Here, we determined the genome sequences of five B. coagulans strains, and used a comparative genomic approach to reconstruct the central carbon metabolism of this species to explain their fermentation features. A novel xylose isomerase in the xylose utilization pathway was identified in these strains. Based on a genome-wide positive selection scan, the selection pressure on amino acid metabolism may have played a significant role in the thermal adaptation. We also researched the immune systems of B. coagulans strains, which provide them with acquired resistance to phages and mobile genetic elements. Our genomic analysis provides comprehensive insights into the genetic characteristics of B. coagulans and paves the way for improving and extending the uses of this species.
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