Evidence map›Paper›PMID 24473143›Full record

ArticleInternational journal of molecular sciences2014

Identification and molecular characterization of a chitin deacetylase from Bombyx mori peritrophic membrane.

Xiao-Wu Zhong, Xiao-Huan Wang, Xiang Tan, Qing-You Xia, Zhong-Huai Xiang, Ping Zhao

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Intestinal Immune Defense System in Insects.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Article
  9. Role ofInternational journal of molecular sciences · 2020
    Article
  10. Immune Functional Analysis ofInternational journal of molecular sciences · 2019
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiao-Wu ZhongState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China. zxw_strive@163.com.
Xiao-Huan WangState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China. wangxiaohuan1024@126.com.
Xiang TanState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China. luffy.tan@gmail.com.
Qing-You XiaState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China. xiaqy@swu.edu.cn.
Zhong-Huai XiangState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China. xbxzh@swu.edu.cn.
Ping ZhaoState Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China. zhaop@swu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The insect midgut epithelium is generally lined with a unique chitin and protein structure, the peritrophic membrane (PM), which facilitates food digestion and protects the gut epithelium. PM proteins are important determinants for PM structure and formation. In this study, the silkworm Bombyx mori midgut PM protein BmCDA7 was identified by proteomic tools. The full-length BmCDA7 cDNA is 1357 bp; the deduced protein is composed of 379 amino acid residues and includes a 16 amino acid residue signal peptide, a putative polysaccharide deacetylase-like domain and 15 cysteine residues present in three clusters. The heterologously expressed proteins of the BmCDA7 gene in yeast displayed chitin deacetylase activity. Expression of B. mori BmCDA7 was detected in the midgut at both the transcriptional and translational levels. The BmCDA7 gene was expressed by the newly hatched silkworm larvae until day seven of the fifth instar and was expressed at a high level in the newly exuviated larvae of different instars. The functions and regulatory mechanism of BmCDA7, however, need further investigation.

Indexed as

Insect ProteinsAmidohydrolasesAmino Acid SequenceAnimalsBase SequenceBombyxEnzyme ActivationGene ExpressionMolecular Sequence DataOrgan SpecificityProtein TransportProteomicsRecombinant ProteinsAmidohydrolaseschitin deacetylaseInsect ProteinsRecombinant Proteins

Identifiers

PMID24473143
PMCPMC3958831

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.