Evidence map›Paper›PMID 24470841›Full record

ArticleACS medicinal chemistry letters2013

Discovery of potent and selective inhibitors of

Nilesh Zaware, Hitesh Sharma, Jie Yang, Ravi Kumar Vyas Devambatla, Sherry F Queener, Karen S Anderson, Aleem Gangjee

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Evaluation ofMetabolites · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. In vitro therapeutic effect ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019
    Article
  8. Article
  9. Article
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  11. Review
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nilesh ZawareDivision of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, United States.
Hitesh SharmaDepartment of Pharmacology, Yale University School of Medicine, New Haven, CT 06511, United States.
Jie YangDivision of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, United States.
Ravi Kumar Vyas DevambatlaDivision of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, United States.
Sherry F QueenerDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN 46202, United States.
Karen S AndersonDepartment of Pharmacology, Yale University School of Medicine, New Haven, CT 06511, United States.
Aleem GangjeeDivision of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, United States.
Duquesne University · USYale University · USIndiana University – Purdue University Indianapolis · US

Funding

Exploring Novel Targeting Strategies for AIDS Protozoal PathogensR01AI083146 · NIAID · YALE UNIVERSITY · PI ANDERSON, KAREN S. · 2010 to 2019
$3.9M
NIAID NIH HHS R01 AI083146
6 · The paper itself

Abstract

Infection by the parasite

Indexed as

Active-site inhibitorsCrystal structureOpportunistic infectionThymidylate-synthase inhibitorsToxoplasma gondii

Identifiers

PMID24470841
PMCPMC3901304
OpenAlexW2050250344

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.