Evidence map›Paper›PMID 24470757›Full record

ArticlePatient preference and adherence2014

Relationship between medication beliefs, self-reported and refill adherence, and symptoms in patients with asthma using inhaled corticosteroids.

Mna Van Steenis, Ja Driesenaar, Jm Bensing, R Van Hulten, Pc Souverein, L Van Dijk, Pagm De Smet, Am Van Dulmen

Abstract read
In one paragraph

Article in Patient preference and adherence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Mode and Frame Matter: Assessing the Impact of Survey Mode and Sample Frame in Choice Experiments.Medical decision making : an international journal of the Society for Medical Decision Making · 2019
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  18. The use of inhaled corticosteroids in pediatric asthma: update.The World Allergy Organization journal · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mna Van SteenisDepartment of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
Ja DriesenaarNIVEL (Netherlands institute for health services research), Utrecht, The Netherlands.
Jm BensingNIVEL (Netherlands institute for health services research), Utrecht, The Netherlands ; Department of Psychology, Faculty of Social and Behavioural Sciences, Utrecht University, Utrecht, The Netherlands.
R Van HultenDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands.
Pc SouvereinDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands.
L Van DijkNIVEL (Netherlands institute for health services research), Utrecht, The Netherlands ; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands.
Pagm De SmetIQ Healthcare, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Am Van DulmenNIVEL (Netherlands institute for health services research), Utrecht, The Netherlands ; Department of Primary and Community Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands ; Department of Health Sciences, Buskerud University College, Drammen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBeliefs play a crucial role in medication adherence. Interestingly, the relationship between beliefs and adherence varies when different adherence measures are used. How adherence, in turn, is related to asthma symptoms is still unclear. Our aim was to investigate the relationship between beliefs (ie, necessities and concerns) about inhaled corticosteroids (ICS) and subjectively as well as objectively measure adherence and the agreement between these measures. Further, the relationship between adherence and asthma symptoms was examined.

methodsA total of 280 patients aged 18-80 years who filled at least two ICS prescriptions in the preceding year were recruited to complete a questionnaire. The questionnaire included the Beliefs about Medicines Questionnaire to assess necessity beliefs and concerns about ICS, four questions about ICS use to measure self-reported adherence, and the Asthma Control Questionnaire to assess asthma symptoms. Proportion of days covered was used to determine pharmacy refill adherence.

resultsData from 93 patients with asthma were analyzed. Necessities were positively related to self-reported adherence (P = 0.01). No other associations were found between beliefs and subjective or objective adherence. There was no correlation between self-reported and refill adherence. Participants were significantly (P < 0.001) less adherent according to self-report data (24.4%) than according to pharmacy data (57.8%). No relationship was found between adherence and asthma symptoms.

conclusionHigher necessities are associated with higher self-reported adherence, suggesting that it could be more important to focus on necessities than on concerns in an attempt to improve adherence. Self-reported and refill adherence measurements cannot be used interchangeably. No relationship between adherence and asthma symptoms was found.

Indexed as

adherenceasthmaasthma symptomsinhaled corticosteroidsmedication beliefs

Identifiers

PMID24470757
PMCPMC3895030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.