ArticleNeuro-oncology2014
Incidence and survival of children with central nervous system primitive tumors in the French National Registry of Childhood Solid Tumors.
Article in Neuro-oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- The global prevalence of primary central nervous system tumors: a systematic review and meta-analysis.European journal of medical research · 2023Pooled it
- Worldwide Trends in Survival From Common Childhood Brain Tumors: A Systematic Review.Journal of global oncology · 2019Pooled it
- Primary Pediatric Brain Tumors in a Tertiary Referral Center in Iran: A 13-Year Retrospective Analysis.Archives of Iranian medicine · 2025Article
- Worldwide patterns and trends in childhood and adolescent brain cancers, 1990-2021: insights from the global burden of disease study 2021.Frontiers in public health · 2025Article
- Extensive Leptomeningeal Spreading of Ependymoma in an Adult: Case Report and Literature Review.Brain tumor research and treatment · 2023Article
- Passive functional mapping of receptive language cortex during general anesthesia using electrocorticography.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023Article
- Childhood cancer survival and avoided deaths in Australia, 1983-2016.Paediatric and perinatal epidemiology · 2023Article
- Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum.International journal of molecular sciences · 2022Article
- Article
- Central nervous system tumors in children under 5 years of age: a report on treatment burden, survival and long-term outcomes.Journal of neuro-oncology · 2022Article
- Incidence and survival of childhood central nervous system tumors in Denmark, 1997-2019.Cancer medicine · 2022Article
- Neuroimaging of paediatric pineal, sellar and suprasellar tumours: a guide to differential diagnosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Review
- H3.3K27M Mutation Controls Cell Growth and Resistance to Therapies in Pediatric Glioma Cell Lines.Cancers · 2021Article
- Incidence and survival for childhood central nervous system tumours in Australia, 1983-2016.Journal of neuro-oncology · 2021Article
- Prevalence, clinical features and prognosis of malignant solid tumors in infants: a 14-year study.Bosnian journal of basic medical sciences · 2021Article
- Real-world data for pediatric medulloblastoma: can we improve outcomes?European journal of pediatrics · 2021Article
- Childhood Cancer Survival in Brunei Darussalam.Asian Pacific journal of cancer prevention : APJCP · 2020Article
- The Role of Time as a Prognostic Factor in Pediatric Brain Tumors: a Multivariate Survival Analysis.Pathology oncology research : POR · 2020Article
- An epidemiology report for primary central nervous system tumors in adolescents and young adults: a nationwide population-based study in France, 2008-2013.Neuro-oncology · 2020Article
- Childhood cancer incidence and survival trends in Estonia (1970-2016): a nationwide population-based study.BMC cancer · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCentral nervous system (CNS) tumors are the second most common childhood malignancy. The French National Registry of Childhood Solid Tumors (NRCST) makes it possible to describe this variety of distinct tumor types and to provide incidence and survival data in France on a nationwide basis.
methodsAll children aged 0-14 years, who were registered with a primary CNS tumor in the NRCST of France between 2000 and 2008, were identified. Tumors were classified according to the International Classification of Childhood Cancer, third edition.
resultsApproximately 57% of pediatric CNS tumors were gliomas, with astrocytomas of the pilocytic type predominating. Distributions of subtypes by age showed that primitive neuroectodermal tumors and ependymomas mainly occurred in children aged <5 years. The mean annual incidence rate of CNS tumors was 39 per million. No statistically significant change in time trends of incidence rate was observed during 2000-2008. For all tumors combined, overall survival was 84.8% (95% CI, 83.7%-85.9%) at 1 year and 72.9% (95% CI, 71.5%-74.3%) at 5 years. Survival time trends were studied in a multivariate analysis observing a reduction in the risk of death in periods of diagnosis 2003-2005 (HR = 0.8; 95% CI, 0.7–0.9) and 2006-2008 (HR = 0.7; 95% CI, 0.6-0.9) compared with 2000-2002.
conclusionsThe stable incidence rates during the last 10 years could indicate that major changes in environmental risk factors are unlikely, but the ongoing need for population-based surveillance remains relevant. Results indicate a positive trend in the survival probability still persistent in the 2000s.
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