Trial reportJournal of clinical oncology : official journal of the American Society of Clinical Oncology2014
Yoga's impact on inflammation, mood, and fatigue in breast cancer survivors: a randomized controlled trial.
Trial report in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 183 papers, 33 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Breast Cancer Survivors: Physical Activity, Inflammation, Fatigue, and Distress
The Acute Impact of Yoga-based Stretching on Inflammation and Its Resolution: a Pilot Study
A Randomized, Open-labelled, Controlled Trial Evaluating the Efficacy of a Physical Therapy-yoga-patient Educational Program for Breast Cancer Patients With Pain Due to Hormonal Therapy Treatment.
Impact of Yoga and Gentle Massage Practices on Symptom Management in Patients Undergoing Hematopoietic Stem Cell Transplantation at the Hospital Israelita Albert Einstein
Who cites it
183 citing papers in PubMed, 33 syntheses or guidelines pooled it, 373 citations in OpenAlex.
- Optimal yoga dose for improving cancer-related fatigue, quality of life, and sleep quality in breast cancer survivors: a Bayesian dose-response meta-analysis.Journal of cancer survivorship : research and practice · 2026Pooled it
- Effects of yoga on depressive symptoms in breast cancer patients: a meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Mind-body exercise for symptom management in cancer: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Optimized exercise prescription for alleviating cancer-related fatigue in breast cancer survivors after primary treatment: a systematic review and dose-response network meta-analysis.Frontiers in public health · 2026Pooled it
- Effects of different exercise interventions on quality of life in breast cancer survivors after treatment: a systematic review and network meta-analysis.Frontiers in oncology · 2026Pooled it
- Pooled it
- Yoga for fatigue in people with cancer.The Cochrane database of systematic reviews · 2025Pooled it
- Comparative Efficacy of Various Exercise Types on Cancer-Related Fatigue for Cancer Survivors: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.Cancer medicine · 2025Pooled it
- The impact of mind-body exercise on female breast cancer patients-a systematic review and meta-analysis of randomized controlled trials.Frontiers in public health · 2025Pooled it
- The effects of aerobic exercise in patients with cancer-related fatigue: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Different exercise interventions on quality of sleep in breast cancer survivors-a network meta-analysis of randomized controlled trials.Frontiers in oncology · 2025Pooled it
- The effect of chronic yoga interventions on sleep quality in people with sleep disorders: a scoping review.Frontiers in neurology · 2025Pooled it
- Management of Fatigue in Adult Survivors of Cancer: ASCO-Society for Integrative Oncology Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Guideline
- Comparative Efficacy of Mind-Body Exercise for Treating Chronic Non-Specific Neck Pain: A Systematic Review and Network Meta-Analysis.Current pain and headache reports · 2024Pooled it
- Impact of exercise interventions on physical fitness in breast cancer patients and survivors: a systematic review.Breast cancer (Tokyo, Japan) · 2022Pooled it
- A systematic review of in vivo stretching regimens on inflammation and its relevance to translational yoga research.PloS one · 2022Pooled it
- Interventions for multidimensional aspects of breast cancer-related fatigue: a meta-analytic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- The effect of yoga on sleep quality and insomnia in women with sleep problems: a systematic review and meta-analysis.BMC psychiatry · 2020Pooled it
- Exercise therapies for preventing or treating aromatase inhibitor-induced musculoskeletal symptoms in early breast cancer.The Cochrane database of systematic reviews · 2020Pooled it
- Impact of Yoga on Inflammatory Biomarkers: A Systematic Review.Biological research for nursing · 2019Pooled it
123 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo evaluate yoga's impact on inflammation, mood, and fatigue. PATIENTS AND
methodsA randomized controlled 3-month trial was conducted with two post-treatment assessments of 200 breast cancer survivors assigned to either 12 weeks of 90-minute twice per week hatha yoga classes or a wait-list control. The main outcome measures were lipopolysaccharide-stimulated production of proinflammatory cytokines interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), and interleukin-1β (IL-1β), and scores on the Multidimensional Fatigue Symptom Inventory-Short Form (MFSI-SF), the vitality scale from the Medical Outcomes Study 36-item Short Form (SF-36), and the Center for Epidemiological Studies-Depression (CES-D) scale.
resultsImmediately post-treatment, fatigue was not lower (P > .05) but vitality was higher (P = .01) in the yoga group compared with the control group. At 3 months post-treatment, fatigue was lower in the yoga group (P = .002), vitality was higher (P = .01), and IL-6 (P = .027), TNF-α (P = .027), and IL-1β (P = .037) were lower for yoga participants compared with the control group. Groups did not differ on depression at either time (P > .2). Planned secondary analyses showed that the frequency of yoga practice had stronger associations with fatigue at both post-treatment visits (P = .019; P < .001), as well as vitality (P = .016; P = .0045), but not depression (P > .05) than simple group assignment; more frequent practice produced larger changes. At 3 months post-treatment, increasing yoga practice also led to a decrease in IL-6 (P = .01) and IL-1β (P = .03) production but not in TNF-α production (P > .05).
conclusionChronic inflammation may fuel declines in physical function leading to frailty and disability. If yoga dampens or limits both fatigue and inflammation, then regular practice could have substantial health benefits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.