Evidence map›Paper›PMID 24468896›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2014

Risk factors for clinical events at 1-year follow-up after drug-eluting stent implantation: results from the prospective multicenter German DES.DE registry.

I Akin, C A Nienaber, G Richardt, R Tölg, M Hochadel, S Schneider, J Senges, U Tebbe, U Zeymer, G Sabin and 2 more

Abstract readEvaluation StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. External validity of the "all-comers" design: insights from the BIOSCIENCE trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2016
    Trial
  3. Trial
  4. Trial
  5. Article
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

I AkinMedizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Deutschland, ibrahim.akin@med.uni-rostock.de.
C A Nienaber
G Richardt
R Tölg
M Hochadel
S Schneider
J Senges
U Tebbe
U Zeymer
G Sabin
K-H Kuck
M W Bergmann
Stiftung Institut für Herzinfarktforschung · DEAsklepios Klinik St. Georg · DESegeberger Kliniken · DEElisabeth-Krankenhaus Essen · DEKlinikum Lippe · DEKlinikum Ludwigshafen · DEMedizinische Fakultät MannheimUniversitätsmedizin Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDrug-eluting stents (DES) have substantially reduced target vessel revascularization (TVR) after percutaneous coronary interventions. Risk factors for clinical events need to be redefined with this treatment option. METHODS AND

resultsIn the prospective DES.DE registry, baseline clinical and angiographic characteristics as well as in-hospital and follow-up events were recorded for all enrolled patients. Between October 2005 and May 2009, 21,774 patients receiving DES were enrolled at 98 DES.DE sites. The composite of death, myocardial infarction (MI) and stroke defined as major adverse cardiac and cerebrovascular events (MACCE) and TVR were predefined as primary endpoints. At 1-year follow-up rates for overall death, MI, stroke, MACCE, TVR and definite stent thrombosis were 2.7, 3.1, 1.4, 7.1, 11.5 and 0.6 %, respectively. Aside from well-known risk factors like age, diabetes mellitus and triple-vessel disease, stratification in patients with or without MACCE revealed atrial fibrillation, non-ST-segment elevation myocardial infarction, renal failure, impaired ejection fraction and peripheral vascular disease as strong predictors of MACCE at 1 year.

conclusionData collected in the DES.DE registry, reflecting the clinical practice in Germany, revealed favorable clinical outcomes after DES implantation in a real world setting but also identifying several high-risk populations.

Indexed as

Drug-Eluting StentsRegistriesAgedAged, 80 and overAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary StenosisFemaleFollow-Up StudiesGermanyGraft Occlusion, VascularHumansIncidenceKaplan-Meier EstimateMaleMiddle Aged

Identifiers

PMID24468896
OpenAlexW1985057763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.