Evidence map›Paper›PMID 24467873›Full record

ArticlePsychiatry research2014

The profile of executive function in OCD hoarders and hoarding disorder.

Sharon Morein-Zamir, Martina Papmeyer, Alberto Pertusa, Samuel R Chamberlain, Naomi A Fineberg, Barbara J Sahakian, David Mataix-Cols, Trevor W Robbins

Abstract read
In one paragraph

Article in Psychiatry research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Cognitive Inflexibility in OCD and Related Disorders.Current topics in behavioral neurosciences · 2021
    Pooled it
  3. Review
  4. Article
  5. The prefrontal cortex and OCD.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
  6. Article
  7. Article
  8. Autistic adults' subjective experiences of hoarding and self-injurious behaviors.Autism : the international journal of research and practice · 2021
    Article
  9. Article
  10. Cognitive performance of individuals with animal hoarding.Health and quality of life outcomes · 2020
    Article
  11. Article
  12. Review
  13. Review
  14. The Brown Incompleteness Scale (BINCS): Measure development and initial evaluation.Journal of obsessive-compulsive and related disorders · 2018
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sharon Morein-ZamirBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK; Department of Psychiatry, University of Cambridge, Cambridge, UK; Department of Psychology, University of Cambridge, Cambridge, UK. Electronic address: sm658@cam.ac.uk.
Martina PapmeyerBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK; Department of Psychology, University of Cambridge, Cambridge, UK.
Alberto PertusaDepartments of Psychology and Psychosis Studies, King's College London, Institute of Psychiatry, London, UK.
Samuel R ChamberlainBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK; Department of Psychiatry, University of Cambridge, Cambridge, UK.
Naomi A FinebergMental Health Unit, QEII Hospital, Welwyn Garden City, Hertfordshire, UK.
Barbara J SahakianBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK; Department of Psychiatry, University of Cambridge, Cambridge, UK.
David Mataix-ColsDepartment of Psychology, University of Cambridge, Cambridge, UK; Departments of Psychology and Psychosis Studies, King's College London, Institute of Psychiatry, London, UK.
Trevor W RobbinsBehavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK; Department of Psychology, University of Cambridge, Cambridge, UK.

Funding

Medical Research Council G0001354Wellcome Trust 089589/Z/09/ZWellcome Trust G00001354
6 · The paper itself

Abstract

Hoarding disorder is a new mental disorder in DSM-5. It is classified alongside OCD and other presumably related disorders in the Obsessive-Compulsive and Related Disorders chapter. We examined cognitive performance in two distinct groups comprising individuals with both OCD and severe hoarding, and individuals with hoarding disorder without comorbid OCD. Participants completed executive function tasks assessing inhibitory control, cognitive flexibility, spatial planning, probabilistic learning and reversal and decision making. Compared to a matched healthy control group, OCD hoarders showed significantly worse performance on measures of response inhibition, set shifting, spatial planning, probabilistic learning and reversal, with intact decision making. Despite having a strikingly different clinical presentation, individuals with only hoarding disorder did not differ significantly from OCD hoarders on any cognitive measure suggesting the two hoarding groups have a similar pattern of cognitive difficulties. Tests of cognitive flexibility were least similar across the groups, but differences were small and potentially reflected subtle variation in underlying brain pathology together with psychometric limitations. These results highlight both commonalities and potential differences between OCD and hoarding disorder, and together with other lines of evidence, support the inclusion of the new disorder within the new Obsessive-Compulsive and Related Disorders chapter in DSM-5.

Indexed as

AdultCase-Control StudiesCognitionComorbidityCompulsive BehaviorDecision MakingExecutive FunctionFemaleHoarding DisorderHumansInhibition, PsychologicalMaleObsessive-Compulsive DisorderPsychiatric Status Rating ScalesPsychometricsCognitionHoardingHoarding disorderObsessive compulsive disorder (OCD)

Identifiers

PMID24467873
PMCPMC3988927

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.