ArticleBiomedical optics express2013
Depth-resolved model-based reconstruction of attenuation coefficients in optical coherence tomography.
Article in Biomedical optics express, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers.
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Who cites it
186 citing papers in PubMed.
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- Comparing the Effects of Chemical Optical Clearing Agents and Mechanical Compression on the Optical Attenuation of Porcine Skin.Journal of biophotonics · 2026Article
- Optical coherence tomography enables optical biopsy of endometrial tissue for early cancer detection.Npj imaging · 2026Article
- Registration-Based Analysis of the Three-Dimensional Shape of the Retinal Nerve Fiber Layer for Detection of Glaucomatous Defects.Translational vision science & technology · 2026Article
- Estimating the optical properties of corneal tissue from the OCT speckle.Biomedical optics express · 2026Article
- Hybrid particle-wave Monte Carlo OCT simulation method provides a three orders of magnitude improvement in efficiency.Biomedical optics express · 2026Article
- Impact of Scattering Variation Measured by Line-Field Confocal Optical Coherence Tomography on Fluorescence Measurement by Optical Spectroscopy: A Study on Phantoms and Human Skin Models.Skin pharmacology and physiology · 2025Article
- Depth-Resolved Attenuation Coefficient Quantification During Murine Embryonic Brain Development.Journal of biophotonics · 2025Article
- Segmental airway adenocarcinoma-simulating phantom for endoscopic near-infrared optical coherence tomography.Journal of biomedical optics · 2025Article
- Leveraging pretrained vision transformers for automated cancer diagnosis in optical coherence tomography images.Biomedical optics express · 2025Article
- Evaluation of retinal pigment epithelium changes in serous pigment epithelial detachment using synthesized multi-contrast polarization-sensitive optical coherence tomography.Scientific reports · 2025Article
- Quantitative assessment of retinal attenuation and backscattering in OCT imaging using iterative layer-based analysis.Biomedical optics express · 2025Article
- Improving occlusal caries detection using optical clearing agent for optical coherence tomography.Lasers in medical science · 2025Article
- A joint learning approach for automated diagnosis of keratinocyte carcinoma using optical attenuation coefficients.NPJ digital medicine · 2025Article
- Optical Coherence Tomography Angiography, Elastography, and Attenuation Imaging for Evaluation of Liver Regeneration.Diagnostics (Basel, Switzerland) · 2025Article
126 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
We present a method, based on a single scattering model, to calculate the attenuation coefficient of each pixel in optical coherence tomography (OCT) depth profiles. Numerical simulations were used to determine the model's response to different depths and attenuation coefficients. Experiments were performed on uniform and layered phantoms with varying attenuation coefficients. They were measured by a 1300 nm OCT system and their attenuation coefficients were evaluated by our proposed method and by fitting the OCT slope as the gold standard. Both methods showed largely consistent results for the uniform phantoms. On the layered phantom, only our proposed method accurately estimated the attenuation coefficients. For all phantoms, the proposed method largely reduced the variability of the estimated attenuation coefficients. The method was illustrated on an in-vivo retinal OCT scan, effectively removing common imaging artifacts such as shadowing. By providing localized, per-pixel attenuation coefficients, this method enables tissue characterization based on attenuation coefficient estimates from OCT data.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.