ArticlePloS one2014
The temporal evolution and global spread of Cauliflower mosaic virus, a plant pararetrovirus.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 60 citations in OpenAlex.
- Article
- Genome sequence of dahlia mosaic virus revisited: molecular characterization and genetic diversity of DMV and dahlia common mosaic virus.Archives of virology · 2025Article
- Metagenomics-based novel Caulimoviridae virus discovery and its development of identification markers in Lilium lancifolium thunb.Virology journal · 2025Article
- Article
- Determinants of Virus Variation, Evolution, and Host Adaptation.Pathogens (Basel, Switzerland) · 2022Review
- Functional analysis of a viral promoter from a strawberry vein banding virus isolate from China.Virology journal · 2022Article
- Molecular characterization of strawberry vein banding virus from China and the development of loop‑mediated isothermal amplification assays for their detection.Scientific reports · 2022Article
- The recombinogenic history of turnip mosaic potyvirus reveals its introduction to Japan in the 19th century.Virus evolution · 2022Article
- Complete Genome Sequence of Isolate Bari 1, a Mild Strain of Cauliflower Mosaic Virus.Microbiology resource announcements · 2021Article
- Genomic analysis of the brassica pathogen turnip mosaic potyvirus reveals its spread along the former trade routes of the Silk Road.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Enhancing Capsid Proteins Capacity in Plant Virus-Vector Interactions and Virus Transmission.Cells · 2021Review
- Article
- Genetic differences between Korean and American isolates of Petunia vein clearing virus.Virus genes · 2020Article
- Ancient Endogenous Pararetroviruses in Oryza Genomes Provide Insights into the Heterogeneity of Viral Gene Macroevolution.Genome biology and evolution · 2018Article
- Euphyllophyte Paleoviruses Illuminate Hidden Diversity and Macroevolutionary Mode of Caulimoviridae.Journal of virology · 2018Article
- Article
- The Timescale of Emergence and Spread of Turnip Mosaic Potyvirus.Scientific reports · 2017Article
- Cauliflower mosaic virus Transcriptome Reveals a Complex Alternative Splicing Pattern.PloS one · 2015Article
- The effect of ecosystem biodiversity on virus genetic diversity depends on virus species: A study of chiltepin-infecting begomoviruses in Mexico.Virus evolution · 2015Article
- Article
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
9 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cauliflower mosaic virus (CaMV) is a plant pararetrovirus with a double-stranded DNA genome. It is the type member of the genus Caulimovirus in the family Caulimoviridae. CaMV is transmitted by sap inoculation and in nature by aphids in a semi-persistent manner. To investigate the patterns and timescale of CaMV migration and evolution, we sequenced and analyzed the genomes of 67 isolates of CaMV collected mostly in Greece, Iran, Turkey, and Japan together with nine published sequences. We identified the open-reading frames (ORFs) in the genomes and inferred their phylogeny. After removing recombinant sequences, we estimated the substitution rates, divergence times, and phylogeographic patterns of the virus populations. We found that recombination has been a common feature of CaMV evolution, and that ORFs I-V have a different evolutionary history from ORF VI. The ORFs have evolved at rates between 1.71 and 5.81×10(-4) substitutions/site/year, similar to those of viruses with RNA or ssDNA genomes. We found four geographically confined lineages. CaMV probably spread from a single population to other parts of the world around 400-500 years ago, and is now widely distributed among Eurasian countries. Our results revealed evidence of frequent gene flow between populations in Turkey and those of its neighboring countries, with similar patterns observed for Japan and the USA. Our study represents the first report on the spatial and temporal spread of a plant pararetrovirus.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.