Evidence map›Paper›PMID 24465270›Full record

ReviewTheranostics2014

MicroRNA-206: a promising theranostic marker.

Jan Novák, Peter Kružliak, Julie Bienertová-Vašků, Ondřej Slabý, Miroslav Novák

Open access · goldAbstract readReview
In one paragraph

Review in Theranostics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 56 citations in OpenAlex.

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  6. Stanniocalcin 2 (STC2): a universal tumour biomarker and a potential therapeutical target.Journal of experimental & clinical cancer research : CR · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jan Novák1. International Clinical Research Center, Department of Cardiovascular Diseases, St. Anne's University Hospital Brno, Brno, Czech Republic ; 2. Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic ; 3. Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Peter Kružliak1. International Clinical Research Center, Department of Cardiovascular Diseases, St. Anne's University Hospital Brno, Brno, Czech Republic.
Julie Bienertová-Vašků3. Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic ; 4. Molecular Oncology II, Central European Institute of Technology, Brno, Czech Republic.
Ondřej Slabý4. Molecular Oncology II, Central European Institute of Technology, Brno, Czech Republic.
Miroslav Novák1. International Clinical Research Center, Department of Cardiovascular Diseases, St. Anne's University Hospital Brno, Brno, Czech Republic.
Masaryk University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRs) are small non-coding RNAs that negatively regulate gene expression by binding to the 3` untranslated regions (3`UTR) of their target mRNAs. MiRs were shown to play pivotal roles in tissue development and function and are also involved in the pathogenesis of various diseases including cancer. MicroRNA-206, which belongs to the group of so-called "myomiRs", is one of the most studied miRs thus far. In addition to being involved in skeletal muscle development and pathology, it has also been established that it is involved in the pathogenesis of numerous diseases including heart failure, chronic obstructive pulmonary disease, Alzheimer's disease and various types of cancers. The aim of this review is to provide a complex overview of microRNA-206, including regulating its expression, a brief description of its known functions in skeletal muscle and a complex overview of its roles in the biology and pathology of other tissues, emphasizing its significant diagnostic and therapeutic potential.

Indexed as

Alzheimer DiseaseBiological ProductsBiomarkersHeart FailureHumansMicroRNAsMuscle, SkeletalNeoplasmsPulmonary Disease, Chronic ObstructiveBiological ProductsBiomarkersMicroRNAsMIRN206 microRNA, humanmicroRNA-206Theranostic Marker

Identifiers

PMID24465270
PMCPMC3900797
OpenAlexW2123195417

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.