ArticleObesity (Silver Spring, Md.)2014
The relationship between body fat mass percentiles and inflammation in children.
Article in Obesity (Silver Spring, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 62 citations in OpenAlex.
- Trial
- Subclinical inflammation in children with Down syndrome: implications for preventive care.Annals of pediatric endocrinology & metabolism · 2026Article
- Childhood obesity: The threatening apprentice of the adiposity empire.Reviews in endocrine & metabolic disorders · 2025Review
- Associations Between Urinary Pesticide Metabolites and Serum Inflammatory Biomarkers in Adolescents Living in an Agricultural Region.Exposure and health · 2025Article
- Mediating role of inflammatory markers (NLR, PLR, SII, SIRI) in the association between 25(OH)D deficiency and obesity in children and adolescents.Journal of health, population, and nutrition · 2025Article
- National Survey on the Prevalence and Geospatial Variation of Body Fat Percentage Among Preschoolers - 31 PLADs, China, 2020.China CDC weekly · 2025Article
- Association between systemic immune-inflammation index and central obesity in pediatric populations: a cross-sectional and cohort study.Frontiers in immunology · 2025Article
- On the trail of the obesity paradox.Annals of translational medicine · 2022Article
- Exercise Outcomes in Childhood Obesity-Related Inflammation and Oxidative Status.Frontiers in nutrition · 2022Review
- Influence of changes in body fat on clinical outcomes in a general population: a 12-year follow-up report on the Ansan-Ansung cohort in the Korean Genome Environment Study.Annals of medicine · 2021Article
- Relationship between the mitochondria-derived peptide MOTS-c and insulin resistance in obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2021Article
- Inflammation-related plasma protein levels and association with adiposity measurements in young adults.Scientific reports · 2021Article
- Hyperuricemia, Elevated Body Mass Index, Female Sex, and Albuminuria Increase the Probability of Elevated High-Sensitivity C-Reactive Protein: Results From the National Health and Nutrition Examination Survey 2015-2018.Frontiers in public health · 2021Article
- Placental programming, perinatal inflammation, and neurodevelopment impairment among those born extremely preterm.Pediatric research · 2021Review
- Neonatal Adiposity and Childhood Obesity.Pediatrics · 2020Article
- Outcomes and Resource Use Among Overweight and Obese Children With Sepsis in the Pediatric Intensive Care Unit.Journal of intensive care medicine · 2020Article
- Role of tri-ponderal mass index in cardio-metabolic risk assessment in children and adolescents: compared with body mass index.International journal of obesity (2005) · 2020Article
- Enhanced Myeloid Leukocytes in Obese Children and Adolescents at Risk for Metabolic Impairment.Frontiers in endocrinology · 2020Article
- A Multidisciplinary Intervention in Childhood Obesity Acutely Improves Insulin Resistance and Inflammatory Markers Independent From Body Composition.Frontiers in pediatrics · 2020Article
- Oxidative stress in obese children and adolescents with and without type 2 diabetes mellitus is not associated with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveObesity has been associated with markers of increased systemic inflammation in both human and animal studies. Increased inflammation is linked to metabolic and cardiovascular disease. The objective of this study was to evaluate the association between percentile body fat and inflammation in a nationally representative sample of US children.
methods6,950 children 8-18 years of age between 1999 and 2004 were studied. Measurement of body fat percentage was measured by dual-energy X-ray absorptiometry scan and converted to an age- and sex-adjusted percentile. The main outcome measures were abnormal c-reactive protein (CRP > 1.0 mg/dl) and absolute neutrophil count (ANC > 6,600).
resultsChildren with higher levels of body fat (≥70th percentile) had a higher odds of having elevated CRP (OR 2.88-10.69) and elevated ANC (OR 2.14-3.24) compared with children with body fat <70th percentile.
conclusionsThe link between inflammation and body fat in children warrants further longitudinal research to understand the temporal relationship between overweight/obesity and inflammation in the pediatric obese population and its implications for chronic disease risk.
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