ReviewPsychopharmacology2014
Reducing substance use during adolescence: a translational framework for prevention.
Review in Psychopharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 70 citations in OpenAlex.
- Short-Term Intervention Effects of the PATHS Curriculum in Young Low-Income Children: Capitalizing on Plasticity.The journal of primary prevention · 2016Trial
- A randomized, controlled trial of the family check-up model in public secondary schools: Examining links between parent engagement and substance use progressions from early adolescence to adulthood.Journal of consulting and clinical psychology · 2016Trial
- Associations Between Youth Marijuana and Alcohol Use, Neurocognitive Performance, and Triple-Network Resting-State Connectivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Young Adults Coping with Sibling Loss: Risk and Protective Factors for Substance Use Disorder.Journal of child & adolescent trauma · 2026Article
- Latent Classes of Nonmedical Prescription Tranquilizer Use Motives in US Adolescents and Young Adults.Substance use & addiction journal · 2026Article
- Directory of Public Datasets for Youth Mental Health to Enhance Research Through Data, Accessibility, and Artificial Intelligence: Scoping Review.JMIR mental health · 2025Article
- Diagnosing Adolescent Substance Use and Co-Occurring Disorders Using the Global Appraisal of Individual Needs Quick Version-4.Psychiatric research and clinical practice · 2024Article
- Adaptation in Young Military Recruits: Protocol for the Advancing Research on Mechanisms of Resilience (ARMOR) Prospective Longitudinal Study.JMIR research protocols · 2023Article
- Methodological Strategies for Prospective Harmonization of Studies: Application to 10 Distinct Outcomes Studies of Preventive Interventions Targeting Opioid Misuse.Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Dysregulated Emotion and Trying Substances in Childhood: Insights from a Large Nationally Representative Cohort Study.Substance use & misuse · 2023Article
- Cocaine reward and reinstatement in adolescent versus adult rodents.Frontiers in behavioral neuroscience · 2023Review
- Dimensional model on how familial vulnerability and environmental factors impact transitional age youth psychopathology: TheFrontiers in psychiatry · 2023Article
- The role of trauma and positive youth development in polysubstance use among rural middle school students: a latent class analysis.BMC public health · 2022Article
- A Review of the Prevention of Drug Addiction: Specific Interventions, Effectiveness, and Important Topics.Addiction & health · 2022Review
- "I Grew Up Amidst Alcohol and Drugs:" a Qualitative Study on the Lived Experiences of Parental Substance Use Among Adults Who Developed Substance Use Disorders Themselves.Frontiers in psychiatry · 2022Article
- Capitalizing on Neuroplasticity Across Development to Redirect Pathways from Juvenile Justice Involvement.Current topics in behavioral neurosciences · 2022Review
- Adolescent cocaine induced persistent negative affect in female rats exposed to early-life stress.Psychopharmacology · 2021Article
- Factors modulating the incubation of drug and non-drug craving and their clinical implications.Neuroscience and biobehavioral reviews · 2021Review
- Brief Underage Alcohol Use Screener Scores Predict Health Risk Behaviors.The Journal of school nursing : the official publication of the National Association of School Nurses · 2021Article
- Increased negative affect when combining early-life maternal deprivation with adolescent, but not adult, cocaine exposure in male rats: regulation of hippocampal FADD.Psychopharmacology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
rationaleMost substance use is initiated during adolescence when substantial development of relevant brain circuitry is still rapidly maturing. Developmental differences in reward processing, behavioral flexibility, and self-regulation lead to changes in resilience or vulnerability to drugs of abuse depending on exposure to risk factors. Intervention and prevention approaches to reducing addiction in teens may be able to capitalize on malleable brain systems in a predictable manner.
objectiveThis review will highlight what is known about how factors that increase vulnerability to addiction, including developmental stage, exposure to early life adversity (ranging from abuse, neglect, and bullying), drug exposure, and genetic predisposition, impact the development of relevant systems. RESULTS AND
conclusionsAppropriate, early intervention may restore the normal course of an abnormal trajectory and reduce the likelihood of developing a substance use disorder (SUD) later in life. A considerable amount is known about the functional neuroanatomy and/or pharmacology of risky behaviors based on clinical and preclinical studies, but relatively little has been directly translated to reduce their impact on addiction in high-risk children or teenagers. An opportunity exists to effectively intervene before adolescence when substance use is likely to emerge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.