Evidence map›Paper›PMID 24461458›Full record

ReviewClinical breast cancer2014

Effect of age and race on quality of life in young breast cancer survivors.

Phuong Khanh Morrow, Anita C Broxson, Mark F Munsell, Karen Basen-Enquist, Carol K Rosenblum, Leslie R Schover, Lynne H Nguyen, Limin Hsu, Lilibeth Castillo, Karin M Hahn and 3 more

Abstract readReview
In one paragraph

Review in Clinical breast cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Long-term health-related quality of life among adolescent and young adult breast cancer survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  6. Longitudinal changes of health-related quality of life over 10 years in breast cancer patients treated with radiotherapy following breast-conserving surgery.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  7. Article
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  11. Financial worry and psychological distress among cancer survivors in the United States, 2013-2018.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Phuong Khanh MorrowDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address: pmorrow@amgen.com.
Anita C BroxsonDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Mark F MunsellDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX.
Karen Basen-EnquistDepartment of Behavioral Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX.
Carol K RosenblumDepartment of Behavioral Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX.
Leslie R SchoverDepartment of Behavioral Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX.
Lynne H NguyenDepartment of Health Disparities Research, The University of Texas MD Anderson Cancer Center, Houston, TX.
Limin HsuDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Lilibeth CastilloDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Karin M HahnDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Jennifer K LittonDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Danielle N KwiatkowskiDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Gabriel N HortobagyiDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Kathrin Milbury · 1985 to 2026
$290.8M
TRAINING FOR ACADEMIC ONCOLOGY/HEMATOLOGYT32CA009666 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Michael Davies, Courtney DiNardo · 1994 to 2026
$9.8M
NCI NIH HHS CA 16672NCI NIH HHS P30 CA016672NCI NIH HHS T32 CA009666
6 · The paper itself

Abstract

backgroundGiven their early age at diagnosis, young breast cancer survivors (YBCSs) face issues that differ widely from their older counterparts. PATIENTS AND

methodsWe mailed a survey to 2209 patients who were ≤ 45 years at the time of breast cancer (BC) diagnosis. Each survey was composed of the Quality of Life in Adult Cancer Survivors instrument, Menopause Symptom Scale, and questions aimed at obtaining pertinent background information.

resultsOne thousand ninety patients completed the survey. Mean age at time of diagnosis was 39.5 years; median years from diagnosis was 6.6 years. Distress related to vaginal dryness (P = .0002) and pain from intercourse (P = .0014) was significantly higher in patients who were < 5 years from diagnosis compared with those > 10 years from diagnosis. In the area of financial problems, black women had greater distress than did white women (P = .0010). Compared with white women, Hispanic women had worse family distress scores (P = .0028) and summary cancer-specific scores (P = .0076). Patients > 10 years from diagnosis had less sexual interest (P = .003) than did women who were closer to diagnosis. Women ≥ 40 years at diagnosis had significantly lower sexual interest (P = .0016) than did women < 40 years. Stage and neoadjuvant chemotherapy did not have a significant effect on quality of life (QOL).

conclusionEven in comparison to stage and neoadjuvant chemotherapy, race, age at diagnosis, and time from diagnosis have significant long-term effects on QOL after treatment for BC.

Indexed as

Quality of LifeRacial GroupsAdultAgedAge FactorsBreast NeoplasmsEthnicityFemaleHumansMiddle AgedNeoplasm StagingSurveys and QuestionnairesSurvivorsAge at diagnosisSurveyYears from diagnosis

Identifiers

PMID24461458
PMCPMC4157133

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.