Evidence map›Paper›PMID 24460846›Full record

ArticleJournal of clinical nursing2014

Symptom cluster, healthcare use and mortality in patients with severe chronic obstructive pulmonary disease.

Soo Kyung Park, Janet L Larson

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical nursing, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Association of Patient-Reported Outcome Patterns and Major Clinical Factors with Frailty in Stable COPD.International journal of chronic obstructive pulmonary disease · 2025
    Article
  8. Symptom phenotyping in people with cystic fibrosis during acute pulmonary exacerbations using machine-learning K-means clustering analysis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2024
    Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. A Proposed Theory of Symptom Cluster Management.Belitung nursing journal · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Observational
  18. Distinct symptom experiences in subgroups of patients with COPD.International journal of chronic obstructive pulmonary disease · 2016
    Article
  19. Effect of symptoms on physical performance in COPD.Heart & lung : the journal of critical care
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Soo Kyung ParkSchool of Nursing, Korea University, Seoul, Korea.
Janet L Larson
Korea University · KRUniversity of Michigan–Ann Arbor · US

Funding

Health Promotion/Risk Reduction Interventions with Vulnerable PopulationsT32NR007073 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VILLARRUEL, ANTONIA M. · 1992 to 2012
$4.1M
NINR NIH HHS T32 NR007073
6 · The paper itself

Abstract

AIMS AND

objectivesTo examine how subgroups of patients with chronic obstructive pulmonary disease, identified by ratings of symptoms (dyspnoea, anxiety, depression and fatigue), affect healthcare use and mortality.

backgroundPeople with chronic obstructive pulmonary disease often experience multiple symptoms. The importance of multiple symptoms and symptom clusters has received increased attention. However, little is known about symptom clusters and their effect on healthcare use and mortality in this population.

designDescriptive cross-sectional study.

methodsThis secondary data analysis used data from the National Emphysema Treatment Trial. Participants (n = 597) had severe chronic obstructive pulmonary disease. Descriptive and inferential statistics were used to analyse the data that were drawn from structured interviews, questionnaires and clinical measures.

resultsThree subgroup clusters emerged based on four symptom ratings. Mean age, proportion with higher education, proportion using oxygen, disease severity, exercise capacity and quality of life differed significantly between subgroups. Participants with high levels of symptoms used healthcare services more and were more likely to have died at the five-year follow-up than those with low levels of symptoms. Symptom cluster subgroups had more significant relationship with mortality than single symptoms.

conclusionPatients with high levels of symptoms require greater clinical attention. RELEVANCE TO CLINICAL PRACTICE: Understanding subgroups of patients, based on symptom ratings and their adverse effect on outcomes, may enable healthcare providers to assess multiple symptoms and identify subgroups of patients at risk of increased healthcare use and mortality. Targeting modifiable symptoms within the cluster may be more beneficial than focusing on a single symptom for certain health-related outcome.

Indexed as

Patient Acceptance of Health CareQuality of LifeAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveSeverity of Illness IndexSurveys and Questionnaireschronic obstructive pulmonary diseasehealthcare usemortalityNational Emphysema Treatment Trialsymptoms

Identifiers

PMID24460846
PMCPMC4108559
OpenAlexW2002864976

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.