ArticleClinical and molecular hepatology2013
Ultrasonographic scoring system score versus liver stiffness measurement in prediction of cirrhosis.
Article in Clinical and molecular hepatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Diagnostic Accuracy of Hepatic Vein Arrival Time Performed with Contrast-Enhanced Ultrasonography for Cirrhosis: A Systematic Review and Meta-Analysis.Gut and liver · 2017Pooled it
- Ultrasonography for diagnosis of alcoholic cirrhosis in people with alcoholic liver disease.The Cochrane database of systematic reviews · 2016Pooled it
- The accuracy of ultrasonography for the evaluation of portal hypertension in patients with cirrhosis: a systematic review.Korean journal of radiologyPooled it
- Bile acid profiles in adult patients with biliary atresia who achieve native liver survival after portoenterostomy.Scientific reports · 2024Article
- Article
- Application of ultrasound for the diagnosis of cirrhosis/portal hypertension.Journal of medical ultrasonics (2001) · 2022Review
- Combination of FIB-4 with ultrasound surface nodularity or elastography as predictors of histologic advanced liver fibrosis in chronic liver disease.Scientific reports · 2021Article
- Combining hepatic surface nodularity and serum tests better predicts hepatic fibrosis stages in chronic liver disease.Abdominal radiology (New York) · 2021Article
- Ultrasonographic grayscale findings related to fibrosis in patients with non-alcoholic fatty liver disease: comparison with transient elastography and Fib-4 index.Journal of medical ultrasonics (2001) · 2021Article
- Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use.World journal of gastroenterology · 2021Review
- Noninvasive Assessment of Hepatitis C Virus Infected Patients Using Vibration-Controlled Transient Elastography.Journal of clinical medicine · 2021Review
- Ultrasonographic morphological diagnosis of chronic liver disease: 2-dimensional shear wave elastography as an add-on test.Ultrasonography (Seoul, Korea) · 2020Article
- Severity of Fontan-Associated Liver Disease Correlates with Fontan Hemodynamics.Pediatric cardiology · 2020Article
- Current Perspectives Regarding Stem Cell-Based Therapy for Liver Cirrhosis.Canadian journal of gastroenterology & hepatology · 2018Review
- An endoplasmic reticulum protein, Nogo-B, facilitates alcoholic liver disease through regulation of kupffer cell polarization.Hepatology (Baltimore, Md.) · 2017Article
- 2D Shear Wave Elastography of Liver in Patients with Primary Extrahepatic Portal Vein Obstruction.Journal of clinical and experimental hepatology · 2017Article
- Therapeutic Effect and Location of GFP-Labeled Placental Mesenchymal Stem Cells on Hepatic Fibrosis in Rats.Stem cells international · 2017Article
- Multipotent mesenchymal stromal cells: A promising strategy to manage alcoholic liver disease.World journal of gastroenterology · 2016Review
- Mesenchymal stem cell therapy for cirrhosis: Present and future perspectives.World journal of gastroenterology · 2015Review
- Mesenchymal stem cell therapy for liver fibrosis.The Korean journal of internal medicine · 2015Review
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Authors and funding
12 authors.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsWe compared the cirrhosis-prediction accuracy of an ultrasonographic scoring system (USSS) combining six representative sonographic indices with that of liver stiffness measurement (LSM) by transient elastography, and prospectively investigated the correlation between the USSS score and LSM in predicting cirrhosis.
methodsTwo hundred and thirty patients with chronic liver diseases (187 men, 43 women; age, 50.4±9.5 y, mean±SD) were enrolled in this prospective study. The USSS produces a combined score for nodularity of the liver surface and edge, parenchyma echogenicity, presence of right-lobe atrophy, spleen size, splenic vein diameter, and abnormality of the hepatic vein waveform. The correlations of the USSS score and LSM with that of a pathological liver biopsy (METAVIR scoring system: F0-F4) were evaluated.
resultsThe mean USSS score and LSM were 7.2 and 38.0 kPa, respectively, in patients with histologically overt cirrhosis (F4, P=0.017) and 4.3 and 22.1 kPa in patients with fibrotic change without overt cirrhosis (F0-F3) (P=0.025). The areas under the receiver operating characteristic (ROC) curves of the USSS score and LSM for F4 patients were 0.849 and 0.729, respectively. On the basis of ROC curves, criteria of USSS ≥6: LSM ≥17.4 had a sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 89.2%:77.6%, 69.4%:61.4%, 86.5%:83.7%, 74.6%:51.9% and 0.83:0.73, respectively, in predicting F4.
conclusionsThe results indicate that this USSS has comparable efficacy to LSM in the diagnosis of cirrhosis.
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