Evidence map›Paper›PMID 24459533›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2013

Influence of acupuncture stimulation on cerebral network in functional diarrhea.

Siyuan Zhou, Fang Zeng, Jixin Liu, Hui Zheng, Wenjing Huang, Ting Liu, Dashuai Chen, Wei Qin, Qiyong Gong, Jie Tian and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
10.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Role of Traditional Acupuncture in Patients with Fecal Incontinence-Mini-Review.International journal of environmental research and public health · 2021
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Functional Connectivity Modulation by Acupuncture in Patients with Bell's Palsy.Evidence-based complementary and alternative medicine : eCAM · 2016
    Article
  11. The Status of the Quality Control in Acupuncture-Neuroimaging Studies.Evidence-based complementary and alternative medicine : eCAM · 2016
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Siyuan ZhouAcupuncture and Tuina School, The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, No. 37 Shi'er Qiao Road, Chengdu, Sichuan 610075, China.
Fang ZengAcupuncture and Tuina School, The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, No. 37 Shi'er Qiao Road, Chengdu, Sichuan 610075, China.
Jixin LiuSchool of Life Science and Technology, Xidian University, Shaanxi 710071, China.
Hui ZhengAcupuncture and Tuina School, The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, No. 37 Shi'er Qiao Road, Chengdu, Sichuan 610075, China.
Wenjing HuangThe institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, 10117 Berlin, Germany.
Ting LiuAcupuncture and Tuina School, The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, No. 37 Shi'er Qiao Road, Chengdu, Sichuan 610075, China.
Dashuai ChenAcupuncture and Tuina School, The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, No. 37 Shi'er Qiao Road, Chengdu, Sichuan 610075, China.
Wei QinSchool of Life Science and Technology, Xidian University, Shaanxi 710071, China.
Qiyong GongDepartment of Radiology, The Center for Medical Imaging, Huaxi MR Research Center, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China.
Jie TianSchool of Life Science and Technology, Xidian University, Shaanxi 710071, China.
Ying LiAcupuncture and Tuina School, The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, No. 37 Shi'er Qiao Road, Chengdu, Sichuan 610075, China.
Chengdu University of Traditional Chinese Medicine · CNXidian University · CNCharité - Universitätsmedizin Berlin · DESichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acupuncture is a commonly used therapy for treating functional diarrhea (FD), although there is limited knowledge on the mechanism. The objectives of this study were to investigate the differences in brain activities elicited by acupuncture between FD patients and healthy controls (HC) so as to explore the possible mechanism. Eighteen FD patients and eighteen HC received 10 sessions of acupuncture treatment at ST25 acupoints. Functional magnetic resonance imaging (fMRI) scans were, respectively, performed before and after acupuncture. The defecation frequency, Bristol stool form scale (SBFS), and MOS 36-item Short Healthy Survey (SF-36) were employed to evaluate the clinical efficacy. After acupuncture, the FD patients showed a significant decrease in defecation frequency and BSFS score. The regional homogeneity (ReHo) map showed a decrease in the paracentral lobule and postcentral gyrus, and an increase in the angular gyrus, insula, anterior cingulate cortex (ACC), and precuneus in the FD group. Moreover, the changes in ReHo values in the ACC were correlated with the reduction in defecation frequency. Decreasing functional connectivity among the ACC, insula, thalamus, and orbital frontal cortex only existed in the FD group. Conclusively, acupuncture alleviated defecation frequency and improved stool formation in FD patients. The efficacy might result from the regulation of the homeostasis afferent processing network.

Identifiers

PMID24459533
PMCPMC3888684
OpenAlexW1973029176

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.