Evidence map›Paper›PMID 24459480›Full record

ReviewElectrolyte & blood pressure : E & BP2006

Introduction of Organic Anion Transporters (SLC22A) and a Regulatory Mechanism by Caveolins.

Woon Kyu Lee, Sun-Mi Jung, Jin-Oh Kwak, Seok Ho Cha

Open access · bronzeAbstract readReview
In one paragraph

Review in Electrolyte & blood pressure : E & BP, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Woon Kyu LeeDepartment of Laboratory Animal, Medical Research Center, College of Medicine, Yonsei University, Seoul, Korea.
Sun-Mi JungDepartment of Pharmacology and Toxicology, College of Medicine, Inha University, Inchon, Korea.
Jin-Oh KwakDepartment of Pharmacology and Toxicology, College of Medicine, Inha University, Inchon, Korea.
Seok Ho ChaDepartment of Pharmacology and Toxicology, College of Medicine, Inha University, Inchon, Korea.
Inha University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The kidney is an important organ for controlling the volume of body fluids, electrolytic balance and excretion/reabsorption of endogenous and exogenous compounds. Among these renal functions, excretion/reabsorption of endogenous and exogenous substance is very important for the maintenance of physiological homeostasis in the body. Recently discovered organic anion transporters (OAT or SLC22A) have important roles for renal functions. It is well known as drug transporter. Several isoforms belong to SLC22A family. They showed different transport substrate spectrums and different localizations within the kidney. Their gene expressions are changed by some stimulus. The functional transport properties are regulated by protein kinase C. In addition, the function of organic anion transporters are also regulated by protein-protein interaction, such as caveolin which is compositional protein of caveolae structure. In this review, we will give an introduction of organic anion transporters and its regulatory mechanisms.

Indexed as

CaveolinKidneyMultispecific organic anion transporterOrganic anionRenal localizationTubular secretionXenobiotics

Identifiers

PMID24459480
PMCPMC3894546
OpenAlexW2105780105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.