Evidence map›Paper›PMID 24459469›Full record

ArticleCase reports in medicine2013

First trimester typhoid Fever with vertical transmission of salmonella typhi, an intracellular organism.

Marguerite B Vigliani, Anna I Bakardjiev

Open access · goldAbstract read
In one paragraph

Article in Case reports in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. mBio · 2017
    Article
  6. Article
  7. Intracellular Organisms as Placental Invaders.Fetal and maternal medicine review · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Marguerite B ViglianiDepartment of Obstetrics and Gynecology, Warren Alpert Medical School of Brown University, East Providence, RI 02914-5300, USA.
Anna I BakardjievDepartment of Pediatrics, Microbial Pathogenesis and Host Defense Program, University of California, San Francisco, CA 94143-0654, USA.
Brown University · USUniversity of California, San Francisco · US

Funding

Role of Host Cells in Invasive ListeriosisR01AI084928 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BAKARDJIEV, ANNA · 2010 to 2016
$2.7M
NIAID NIH HHS R01 AI084928
6 · The paper itself

Abstract

We report a case in which placental abruption occurred at 16 weeks following first trimester diagnosis and treatment for typhoid fever. Unexpectedly Salmonella enterica serovar Typhi (S. Typhi) was found in fetal tissues at autopsy. Using information from the murine model of typhoid fever in pregnancy, we draw parallels between S. Typhi and L. monocytogenes to develop a plausible hypothesis to explain how this organism was able to cross the placenta in the first trimester to cause abruption, inflammation, and expulsion of the fetus and placenta. We hope that this model for understanding placental infections by the hematogenous route helps to raise awareness that organisms not typically associated with TORCH infection can nevertheless cause placental infection and pregnancy loss.

Identifiers

PMID24459469
PMCPMC3891435
OpenAlexW2113894121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.