Evidence map›Paper›PMID 24459285›Full record

ArticleGenome biology and evolution2014

BuT2 is a member of the third major group of hAT transposons and is involved in horizontal transfer events in the genus Drosophila.

Dirleane Ottonelli Rossato, Adriana Ludwig, Maríndia Deprá, Elgion L S Loreto, Alfredo Ruiz, Vera L S Valente

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Article in Genome biology and evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

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0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Article
  5. Review
  6. Characterization of a novelMobile DNA · 2019
    Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Dirleane Ottonelli RossatoPrograma de Pós-Graduação em Ecologia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil.
Adriana Ludwig
Maríndia Deprá
Elgion L S Loreto
Alfredo Ruiz
Vera L S Valente

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hAT superfamily comprises a large and diverse array of DNA transposons found in all supergroups of eukaryotes. Here we characterized the Drosophila buzzatii BuT2 element and found that it harbors a five-exon gene encoding a 643-aa putatively functional transposase. A phylogeny built with 85 hAT transposases yielded, in addition to the two major groups already described, Ac and Buster, a third one comprising 20 sequences that includes BuT2, Tip100, hAT-4_BM, and RP-hAT1. This third group is here named Tip. In addition, we studied the phylogenetic distribution and evolution of BuT2 by in silico searches and molecular approaches. Our data revealed BuT2 was, most often, vertically transmitted during the evolution of genus Drosophila being lost independently in several species. Nevertheless, we propose the occurrence of three horizontal transfer events to explain its distribution and conservation among species. Another aspect of BuT2 evolution and life cycle is the presence of short related sequences, which contain similar 5' and 3' regions, including the terminal inverted repeats. These sequences that can be considered as miniature inverted repeat transposable elements probably originated by internal deletion of complete copies and show evidences of recent mobilization.

Indexed as

DNA Transposable ElementsGene Transfer, HorizontalAnimalsDrosophilaDrosophila ProteinsEvolution, MolecularPhylogenyTransposasesDNA Transposable ElementsDrosophila ProteinsTransposasesDrosophilahAThorizontal transferMITEtransposase

Identifiers

PMID24459285
PMCPMC3942097

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.