Evidence map›Paper›PMID 24458274›Full record

ArticleBlood2014

Core fucosylation and IgG function in NAIT.

Richard H Aster

Open access · greenAbstract readComment
In one paragraph

Article in Blood, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Richard H AsterBLOODCENTER OF WISCONSIN;
Medical College of Wisconsin · US

Funding

HEMORRHAGIC DISEASESR01HL013629 · NHLBI · VERSITI WISCONSIN, INC. · PI ASTER, RICHARD HERBERT · 1985 to 2019
$8.7M
NHLBI NIH HHS R01 HL013629
6 · The paper itself

Abstract

In this issue of Blood, Kapur et al show that maternal human platelet-specific antigen 1a (HPA 1a)-specific antibodies causing neonatal alloimmune thrombocytopenia (NAIT) possess oligosaccharides that are deficient in "core fucose" residues and appear to be more effective than fucosylated antibodies in promoting phagocytosis of antibody-coated platelets.

Indexed as

Blood PlateletsFemaleHumansImmunoglobulin Fc FragmentsImmunoglobulin GIsoantibodiesPregnancyThrombocytopenia, Neonatal AlloimmuneImmunoglobulin Fc FragmentsImmunoglobulin GIsoantibodies

Identifiers

PMID24458274
PMCPMC3901063
OpenAlexW1973143793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.