ArticleScientific reports2014
Characterization of a setup to test the impact of high-amplitude pressure waves on living cells.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Extracorporeal shock waves effectively suppress colorectal cancer proliferation and growth.Scientific reports · 2025Article
- Shock wave impact on the viability of MDA-MB-231 cells.PloS one · 2020Article
- Dose-dependent and cell type-specific cell death and proliferation following in vitro exposure to radial extracorporeal shock waves.Scientific reports · 2016Article
- Shock Wave-Induced Damage of a Protein by Void Collapse.Biophysical journal · 2016Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The impact of pressure waves on cells may provide several possible applications in biology and medicine including the direct killing of tumors, drug delivery or gene transfection. In this study we characterize the physical properties of mechanical pressure waves generated by a nanosecond laser pulse in a setup with well-defined cell culture conditions. To systematically characterize the system on the relevant length and time scales (micrometers and nanoseconds) we use photon Doppler velocimetry (PDV) and obtain velocity profiles of the cell culture vessel at the passage of the pressure wave. These profiles serve as input for numerical pressure wave simulations that help to further quantify the pressure conditions on the cellular length scale. On the biological level we demonstrate killing of glioblastoma cells and quantify experimentally the pressure threshold for cell destruction.
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