ArticleMolecular psychiatry2014
DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan.
Abstract readEditorialComment
In one paragraph
Article in Molecular psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: a systematic review.Translational psychiatry · 2017Pooled it
- Evaluating historical candidate genes for schizophrenia.Molecular psychiatry · 2015Pooled it
- Recent Reports on Redox Stress-Induced Mitochondrial DNA Variations, Neuroglial Interactions, and NMDA Receptor System in Pathophysiology of Schizophrenia.Molecular neurobiology · 2022Review
- Mutations in DISC1 alter IPNeuronal signaling · 2021Review
- Host-parasite interaction associated with major mental illness.Molecular psychiatry · 2020Article
- Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1.Frontiers in cellular neuroscience · 2020Article
- Disorder Mediated Oligomerization ofThe journal of physical chemistry. B · 2019Article
- Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte-myelin dysfunction.Molecular psychiatry · 2019Article
- Disrupted-in-schizophrenia 1 functional polymorphisms and DGenes, brain, and behavior · 2019Article
- Disrupted-in-schizophrenia 1 overexpression disrupts hippocampal coding and oscillatory synchronization.Hippocampus · 2019Article
- Protein misassembly and aggregation as potential convergence points for non-genetic causes of chronic mental illness.Molecular psychiatry · 2019Review
- Dysregulation of a specific immune-related network of genes biologically defines a subset of schizophrenia.Translational psychiatry · 2019Article
- Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.Biological psychiatry · 2019Article
- Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression.Translational psychiatry · 2018Article
- The effect of the DISC1 Ser704Cys polymorphism on striatal dopamine synthesis capacity: an [18F]-DOPA PET study.Human molecular genetics · 2018Article
- Recent Advances in the Genetics of Schizophrenia.Molecular neuropsychiatry · 2018Review
- Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development.Schizophrenia bulletin · 2018Article
- Using mouse transgenic and human stem cell technologies to model genetic mutations associated with schizophrenia and autism.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- TheOpen biology · 2017Article
- Genetic interaction of DISC1 and Neurexin in the development of fruit fly glutamatergic synapses.NPJ schizophrenia · 2017Article
Corrections and comments
- Comment on
Authors and funding
18 authors.
D J PorteousCentre for Genomic and Experimental Medicine, MRC/University of Edinburgh Institute of Genetics & Molecular Medicine, Western General Hospital, Edinburgh, UK.
P A ThomsonCentre for Genomic and Experimental Medicine, MRC/University of Edinburgh Institute of Genetics & Molecular Medicine, Western General Hospital, Edinburgh, UK.
J K MillarCentre for Genomic and Experimental Medicine, MRC/University of Edinburgh Institute of Genetics & Molecular Medicine, Western General Hospital, Edinburgh, UK.
K L EvansCentre for Genomic and Experimental Medicine, MRC/University of Edinburgh Institute of Genetics & Molecular Medicine, Western General Hospital, Edinburgh, UK.
W HennahInstitute for Molecular Medicine Finland FIMM, Biomedicum Helsinki 2U, Helsinki, Finland.
D C SoaresCentre for Genomic and Experimental Medicine, MRC/University of Edinburgh Institute of Genetics & Molecular Medicine, Western General Hospital, Edinburgh, UK.
S McCarthyCold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
W R McCombieCold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
S J ClapcoteSchool of Biomedical Sciences, University of Leeds, Leeds, UK.
C KorthDepartment of Neuropathology, Heinrich Heine University, Moorenstraße 5, Dusseldorf, Germany.
N J BrandonAstraZeneca Neuroscience iMed, Cambridge, MA, USA.
A SawaJohns Hopkins Schizophrenia Center, Department of Psychiatry Molecular Psychiatry Program, Department of Mental Health, Johns Hopkins University, School of Medicine and Bloomberg School of Public Health, Baltimore, MD, USA.
A KamiyaDepartment of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
J C RoderLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Joseph & Wolf Lebovic Health Complex, Toronto, Ontario, Canada.
S M LawrieDivision of Psychiatry, School of Clinical Sciences, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.
A M McIntoshDivision of Psychiatry, School of Clinical Sciences, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.
D St ClairInstitute of Medical Sciences University of Aberdeen, Aberdeen, UK.
D H BlackwoodInstitute of Medical Sciences University of Aberdeen, Aberdeen, UK.
Funding
Project 3P50MH094268 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SAWA, AKIRA · 2011 to 2020
$19.9MMedical Research Council G0100266Medical Research Council G0600214Medical Research Council G0902166Medical Research Council MR/J004367/1Medical Research Council MR/K026992/1NIMH NIH HHS P50 MH094268
Abstract
PubMed holds no abstract for this paper.
Indexed as
HumansNerve Tissue ProteinsSchizophreniaNerve Tissue Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.