Evidence map›Paper›PMID 24456982›Full record

ArticleCurrent biology : CB2014

X-inactivation: Xist RNA uses chromosome contacts to coat the X.

Karen N Leung, Barbara Panning

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Linking RNA biology to lncRNAs.Genome research · 2015
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Karen N LeungDepartment of Biochemistry and Biophysics, University of California, San Francisco, 600 16th Street, San Francisco, CA 94158, USA; Department of Anatomy, University of California, San Francisco, 600 16th Street, San Francisco, CA 94158, USA.
Barbara PanningDepartment of Biochemistry and Biophysics, University of California, San Francisco, 600 16th Street, San Francisco, CA 94158, USA. Electronic address: Barbara.Panning@ucsf.edu.
University of California, San Francisco · US

Funding

Investigation of X chromosome organization before the onset of X-inactivationR01GM100341 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PANNING, BARBARA · 2012 to 2015
$1.2M
NIGMS NIH HHS R01 GM100341
6 · The paper itself

Abstract

The mechanisms by which Xist RNA associates with the X chromosome to mediate alterations in chromatin structure remain mysterious. Recent genome-wide Xist RNA distribution studies suggest that this long noncoding RNA uses 3-dimensional chromosome contacts to move to its sites of action.

Indexed as

GenomeX Chromosome InactivationAnimalsFemaleMaleRNA, Long NoncodingX ChromosomeRNA, Long Noncoding

Identifiers

PMID24456982
PMCPMC4465072
OpenAlexW2071629194

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.