Evidence map›Paper›PMID 24456538›Full record

ArticleClinical and translational science2014

Public interest in medical research participation: differences by volunteer status and study type.

Enesha M Cobb, Dianne C Singer, Matthew M Davis

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and translational science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

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  8. Evaluation of the cost and effectiveness of diverse recruitment methods for a genetic screening study.Genetics in medicine : official journal of the American College of Medical Genetics · 2019
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  16. Optimizing Enrollment of Patients into Nephrology Research Studies.Clinical journal of the American Society of Nephrology : CJASN · 2016
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Enesha M CobbRobert Wood Johnson Foundation Clinical Scholars Program, University of Michigan, Ann Arbor, Michigan, USA; Department of Emergency Medicine, University of Michigan, Ann Arbor, Michigan, USA; Department of Veterans Affairs, VA Center for Clinical Management and Research, Ann Arbor VA Healthcare System, Ann Arbor, Michigan, USA.
Dianne C Singer
Matthew M Davis
University of Michigan · US

Funding

Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
NCATS NIH HHS 2UL1TR000433-06NCATS NIH HHS UL1 TR000433
6 · The paper itself

Abstract

purposeWe assessed national levels of public interest in medical research participation (MRP) and factors associated with interest as a healthy volunteer; as a diagnosed volunteer; and in seven study types.

methodCross-sectional, Web-based survey of the US population in June 2012. Descriptive statistics estimated interest in MRP and multivariable logistic regression determined associations between respondent-level predictors and interest in MRP.

resultsOf 2,668 respondents (response rate = 61%), 41% were interested in MRP as healthy volunteers and 60% as diagnosed volunteers. Respondents with some college (OR = 1.54, 1.09-2.19) or higher education (OR = 1.86, 1.29-2.70) had higher adjusted odds of interest as healthy volunteers. Non-Hispanic black race (OR = 0.56, 0.37-0.86) and education below high school (OR = 0.57, 0.35-0.92) were associated with lower adjusted odds of interest as diagnosed volunteers. Non-Hispanic black race was associated with lower odds of interest in medication trials as diagnosed volunteers (OR = 0.61, 0.40-0.93).

conclusionsWe found high levels of interest in MRP that contrast with low levels of prior research participation. Interest is higher in medical research involving noninvasive designs. Comparatively lower levels of interest in MRP among non-Hispanic blacks and those with less education raise concerns about disparities in future study enrollment.

Indexed as

Biomedical ResearchClinical Trials as TopicCommunity ParticipationHealthy VolunteersAdolescentAdultFemaleHumansMaleMiddle AgedYoung Adultclinical trial behaviordevicesdrugsHispanicmental healthnon-Hispanic blacknutritionresearch participationvaccinesvolunteer

Identifiers

PMID24456538
PMCPMC4012324
OpenAlexW1574650178

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.