ArticleJournal of medicinal food2014
Red ginseng (Panax ginseng) decreases isoproterenol-induced cardiac injury via antioxidant properties in porcine.
Article in Journal of medicinal food, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Nuanxin capsule for heart failure: A systematic review of randomized controlled trials.Medicine · 2018Pooled it
- The role of ginseng and ginsenosides in ROS and cardiovascular disease.Journal of ginseng research · 2026Review
- Phytochemistry, quality control and biosynthesis in ginseng research from 2021 to 2023: A state-of-the-art review concerning advances and challenges.Chinese herbal medicines · 2024Review
- Ginseng and ginsenosides on cardiovascular and pulmonary diseases; Pharmacological potentials for the coronavirus (COVID-19).Journal of ginseng research · 2024Review
- Article
- Optimization of Fermentation Conditions and Product Identification of a Saponin-Producing Endophytic Fungus.Microorganisms · 2023Article
- Gypensapogenin I Ameliorates Isoproterenol (ISO)-Induced Myocardial Damage through Regulating the TLR4/NF-κB/NLRP3 Pathway.Molecules (Basel, Switzerland) · 2022Article
- Comparison between the Biological Active Compounds in Plants with Adaptogenic Properties (Plants (Basel, Switzerland) · 2021Review
- Research Progress on Oxidative Stress and Its Nutritional Regulation Strategies in Pigs.Animals : an open access journal from MDPI · 2021Review
- Current Status and Limitations of Myocardial Infarction Large Animal Models in Cardiovascular Translational Research.Frontiers in bioengineering and biotechnology · 2021Review
- The antioxidant activities of Korean Red Ginseng (Journal of ginseng research · 2021Review
- Advances in Saponin Diversity ofMolecules (Basel, Switzerland) · 2020Review
- Korean Red Ginseng enhances cardiac hemodynamics on doxorubicin-induced toxicity in rats.Journal of ginseng research · 2020Article
- The non-saponin fraction of Korean Red Ginseng (KGC05P0) decreases glucose uptake and transportJournal of ginseng research · 2020Article
- Chronic saponin treatment attenuates damage to the pancreas in chronic alcohol-treated diabetic rats.Journal of ginseng research · 2017Article
- Panax ginseng and Panax quinquefolius: From pharmacology to toxicology.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2017Review
- Effect of Korean Red Ginseng extraction conditions on antioxidant activity, extraction yield, and ginsenoside Rg1 and phenolic content: optimization using response surface methodology.Journal of ginseng research · 2016Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Red ginseng (RG, Panax ginseng) has been shown to possess various ginsenosides. These ginsenosides are widely used for treating cardiovascular diseases in Asian communities. The present study was designed to evaluate the cardioprotective potential of RG against isoproterenol (ISO)-induced myocardial infarction (MI), by assessing electrocardiographic, hemodynamic, and biochemical parameters. Male porcines were orally administered with RG (250 and 500 mg/kg) or with vehicle for 9 days, with concurrent intraperitoneal injections of ISO (20 mg/kg) on the 8th and 9th day. RG significantly attenuated ISO-induced cardiac dysfunctions as evidenced by improved ventricular hemodynamic functions and reduced ST segment and QRS complex intervals. Also, RG significantly ameliorated myocardial injury parameters such as antioxidants. Malonaldialdehyde formation was also inhibited by RG. Based on the results, it is concluded that RG possesses significant cardioprotective potential through the inhibition of oxidative stress and may serve as an adjunct in the treatment and prophylaxis of MI.
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Registered trials
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