Evidence map›Paper›PMID 24455728›Full record

ReviewBioMed research international2013

Why control activity? Evolutionary selection pressures affecting the development of physical activity genetic and biological regulation.

J Timothy Lightfoot

Abstract readReview
In one paragraph

Review in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. The role of physical activity in the regulation of body weight: The overlooked contribution of light physical activity and sedentary behaviors.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Sex-dependent differences in voluntary physical activity.Journal of neuroscience research · 2017
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

J Timothy LightfootHuffines Institute of Sports Medicine and Human Performance, Health and Kinesiology Department, Texas A&M University, 356 Blocker Building, 4243 TAMU, College Station, TX 77843, USA.

Funding

GENETIC FACTORS RESPONSIBLE FOR EXERCISE ENDURANCER01AR050085 · NIAMS · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI LIGHTFOOT, J TIMOTHY · 2005 to 2009
$1.6M
Control of Physical Activity by Genetic FactorsR15DK061635 · NIDDK · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI LIGHTFOOT, J TIMOTHY · 2003 to 2003
$133k
NIAMS NIH HHS R01 AR050085NIAMS NIH HHS R01AR050085NIDDK NIH HHS R15 DK061635NIDDK NIH HHS R15DK61635
6 · The paper itself

Abstract

The literature strongly suggests that daily physical activity is genetically and biologically regulated. Potential identities of the responsible mechanisms are unclear, but little has been written concerning the possible evolutionary selection pressures leading to the development of genetic/biological controls of physical activity. Given the weak relationship between exercise endurance and activity levels and the differential genomic locations associated with the regulation of endurance and activity, it is probable that regulation of endurance and activity evolved separately. This hypothesis paper considers energy expenditures and duration of activity in hunter/gatherers, pretechnology farmers, and modern Western societies and considers the potential of each to selectively influence the development of activity regulation. Food availability is also considered given the known linkage of caloric restriction on physical activity as well as early data relating food oversupply to physical inactivity. Elucidating the selection pressures responsible for the genetic/biological control of activity will allow further consideration of these pressures on activity in today's society, especially the linkages between food and activity. Further, current food abundance is removing the cues for activity that were present for the first 40,000 years of human evolution, and thus future research should investigate the effects of this abundance upon the mechanisms regulating activity.

Indexed as

Biological EvolutionEnergy MetabolismExerciseFoodGenetic FitnessHumansSelection, Genetic

Identifiers

PMID24455728
PMCPMC3884604

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.