ReviewScientifica2013
The molecular epidemiology of chronic aflatoxin driven impaired child growth.
Review in Scientifica, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- Association Between Aflatoxin Exposure and Haemoglobin, Zinc, and Vitamin A, C, and E Levels/Status: A Systematic Review.Nutrients · 2025Pooled it
- How immediate and significant is the outcome of training on diversified diets, hygiene and food safety? An effort to mitigate child undernutrition in rural Malawi.Public health nutrition · 2018Trial
- The Potential Role of Mycotoxins as a Contributor to Stunting in the SHINE Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015Trial
- Trial
- Local Nixtamalization Processes Reduce Aflatoxin B1 Concentration and Shift Metabolome in Naturally Contaminated Maize.Journal of agricultural and food chemistry · 2026Article
- Prenatal Aflatoxin BToxins · 2026Review
- The Difficulties in Demonstrating That Aflatoxin Reduction Improves Stunting in Developing World Regions.Toxins · 2026Review
- Early Childhood Dietary Exposure of Aflatoxins and Fumonisins in Tanzania: Role in Child Stunting and Possible Interventions (2003-2024).Food science & nutrition · 2025Review
- Aflatoxin MToxins · 2025Article
- Review
- Longitudinal Assessment of Prenatal, Perinatal, and Early-Life Aflatoxin BCurrent developments in nutrition · 2022Article
- Complementary feeding in Kongwa, Tanzania: Findings to inform a mycotoxin mitigation trial.Maternal & child nutrition · 2021Article
- Occurrence of aflatoxin MMycotoxin research · 2021Article
- Aflatoxin Biosynthesis, Genetic Regulation, Toxicity, and Control Strategies: A Review.Journal of fungi (Basel, Switzerland) · 2021Review
- Review
- Aflatoxin exposure among lactating women in southern Ethiopia.Food science & nutrition · 2020Article
- Metabolite V, an epoxide species is a minor circulating metabolite in humans following a single oral dose of deflazacort.Pharmacology research & perspectives · 2020Article
- Determination of aflatoxin MArchives of toxicology · 2020Article
- Protocol for the trial to establish a causal linkage between mycotoxin exposure and child stunting: a cluster randomized trial.BMC public health · 2020Article
- Aflatoxin exposure in utero and birth and growth outcomes in Tanzania.Maternal & child nutrition · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aflatoxins are toxic secondary fungal metabolites that contaminate dietary staples in tropical regions; chronic high levels of exposure are common for many of the poorest populations. Observations in animals indicate that growth and/or food utilization are adversely affected by aflatoxins. This review highlights the development of validated exposure biomarkers and their use here to assess the role of aflatoxins in early life growth retardation. Aflatoxin exposure occurs in utero and continues in early infancy as weaning foods are introduced. Using aflatoxin-albumin exposure biomarkers, five major studies clearly demonstrate strong dose response relationships between exposure in utero and/or early infancy and growth retardation, identified by reduced birth weight and/or low HAZ and WAZ scores. The epidemiological studies include cross-sectional and longitudinal surveys, though aflatoxin reduction intervention studies are now required to further support these data and guide sustainable options to reduce the burden of exposure. The use of aflatoxin exposure biomarkers was essential in understanding the observational data reviewed and will likely be a critical monitor of the effectiveness of interventions to restrict aflatoxin exposure. Given that an estimated 4.5 billion individuals live in regions at risk of dietary contamination the public health concern cannot be over stated.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.