Evidence map›Paper›PMID 24455301›Full record

ArticleISRN cardiology2013

The Role of BNP and CRP in Predicting the Development of Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Surgery.

Nektarios D Pilatis, Zacharias-Alexandros Anyfantakis, Kyriakos Spiliopoulos, Dimitrios Degiannis, Antigoni Chaidaroglou, Georgia Vergou, Konstantina Kimpouri, Dennis V Cokkinos

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Article in ISRN cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nektarios D Pilatis1st Cardiology Department, Onassis Cardiac Surgery Center, Kallithea, 17674 Athens, Greece.
Zacharias-Alexandros Anyfantakis1st Cardiology Department, Onassis Cardiac Surgery Center, Kallithea, 17674 Athens, Greece ; Department of Cardiology, University of Thessaly, Biopolis, P.O. Box 1400, 41110 Larissa, Greece.
Kyriakos SpiliopoulosDepartment of Thoracic and Cardiovascular Surgery, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, P.O. Box 1400, 41110 Larissa, Greece.
Dimitrios Degiannis2nd Molecular Immunopathology Laboratory, Onassis Cardiac Surgery Center, Kallithea, 17674 Athens, Greece.
Antigoni Chaidaroglou2nd Molecular Immunopathology Laboratory, Onassis Cardiac Surgery Center, Kallithea, 17674 Athens, Greece.
Georgia VergouDepartment of Cardiology, University of Thessaly, Biopolis, P.O. Box 1400, 41110 Larissa, Greece.
Konstantina KimpouriDepartment of Thoracic and Cardiovascular Surgery, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, P.O. Box 1400, 41110 Larissa, Greece.
Dennis V Cokkinos1st Cardiology Department, Onassis Cardiac Surgery Center, Kallithea, 17674 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective. To evaluate the association of BNP and CRP with the development of postoperative atrial fibrillation following coronary artery bypass grafting surgery. Methods. The series consists of 125 patients (aged 65 ± 9 years), who underwent isolated CABG-surgery. BNP and CRP levels were measured pre- and 24 hours postoperatively and their correlation to the development of postoperative AF was analyzed. Results. Forty-four patients (35%) developed AF postoperatively. They were significantly older (68 ± 8 versus 63 ± 9, P = 0.01) and predominantly nonsmokers (18% versus 46%, P = 0.004), compared to the non-AF cases. In addition they showed significant higher preoperative mean BNP levels of 629 versus 373 pg/mL (P = 0.019). Postoperative BNP levels were significantly higher in both groups (AF-group: 1032 pg/mL versus non-AF group: 705 pg/mL; P < 0.001), while there was a trend of more increased postoperative levels in AF-cases (P = 0.065). AF-episodes appeared significantly more frequent in the two highest quartiles of BNP levels with 44% (P = 0.035). On the contrary pre- and postoperative CRP levels were not associated with AF. Multivariable analysis revealed only increased preoperative BNP levels as independent predictor for postoperative AF (P = 0.036). Conclusion. Elevated preoperative BNP serum levels are associated with the development of post-CABG AF, while CRP does not seem to be influential.

Identifiers

PMID24455301
PMCPMC3886441

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