ArticleJournal of clinical and experimental dentistry2013
Comparing the antibacterial activity of gaseous ozone and chlorhexidine solution on a tooth cavity model.
Article in Journal of clinical and experimental dentistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 24 citations in OpenAlex.
- Treatment of symptomatic, deep, almost cariously exposed lesions using ozone.Scientific reports · 2021Trial
- Influence of ozone application in the stepwise excavation of primary molars: a randomized clinical trial.Clinical oral investigations · 2020Trial
- Effectiveness of the ozone application in two-visit indirect pulp therapy of permanent molars with deep carious lesion: a randomized clinical trial.Clinical oral investigations · 2019Trial
- Antibacterial Effect of Ozone on Cariogenic Bacteria and Its Potential Prejudicial Effect on Dentin Bond Strength-An In Vitro Study.Pharmaceutics · 2024Article
- Ozonized Hydrogels vs. 1% Chlorhexidine Gel for the Clinical and Domiciliary Management of Peri-Implant Mucositis: A Randomized Clinical Trial.Journal of clinical medicine · 2023Article
- Effect of Chlorhexidine-containing Etch-and-Rinse Adhesives on Dentin Microtensile Bond Strength after Biological Loading.The journal of adhesive dentistry · 2023Article
- Antimicrobial Effect of Ozone Therapy in Deep Dentinal Carious Lesion: A Systematic Review.International journal of clinical pediatric dentistry · 2022Review
- Ozone treatment of recurrent aphthous stomatitis: a double blinded study.Scientific reports · 2016Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the antibacterial activity of gaseous ozone and chlorhexidine solution on a tooth cavity model. STUDY
designTwenty-one human molars were divided into 3 groups. Cavities were then cut into the teeth (4 per tooth, 28 cavities per group). After sterilization, the teeth were left in broth cultures of 106 colony-forming units (CFU) ml-1 of Streptococcus mutans (S. mutans) at 36°C for 48 h. The appropriate treatment followed (group A, control; group B, 2% chlorhexidine solution; and group C, 80s of treatment with ozone, and the cavities were then filled with composite resin. After 72h, the restorations were removed, dentin chips were collected with an excavator, and the total number of microorganisms was determined.
resultsBoth of the treatments significantly reduced the number of S. mutans present compared with the control group and there was a significant difference between the all groups in terms of the amount of the microorganisms grown (p < 0.05). Group B was beter than group C; and group C was better than group A. Moreover, it was found that the amount of the growth in the group of chlorhexidine was significantly less than that of the ozone group (p < 0.05).
conclusionChlorhexidine solution was the antibacterial treatment most efficacious on S. mutans; however, ozone application could be an anlternative cavity disinfection method because of ozone's cavity disinfection activity. Key words:Antibacterial activity, chlorhexidine, ozone, streptococcus mutans, tooth cavity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.