Trial reportPloS one2014
Fasting for 24 hours heightens reward from food and food-related cues.
Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Trial
- Influence of Short-Term Hyperenergetic, High-Fat Feeding on Appetite, Appetite-Related Hormones, and Food Reward in Healthy Men.Nutrients · 2020Trial
- Factors influencing the reinforcing value of fruit and unhealthy snacks.European journal of nutrition · 2017Trial
- A hypothalamic circuit links hunger to mesolimbic dopamine to drive feeding.bioRxiv : the preprint server for biology · 2026Article
- AgRP neuron activity enhances reward-related consummatory behaviors during energy deficit in mice.Communications biology · 2025Article
- Article
- The impact of hunger on indulgent food choices is moderated by healthy eating concerns.Frontiers in nutrition · 2024Article
- Postprandial Increases in Liver-Gut Hormone LEAP2 Correlate with Attenuated Eating Behavior in Adults Without Obesity.Journal of the Endocrine Society · 2023Article
- Appetite Changes in Weight Regain and Weight Maintenance After Roux-en-Y Gastric Bypass.Obesity surgery · 2022Article
- Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum.eLife · 2022Article
- Article
- How Experiences Affect Psychological Responses During Supervised Fasting: A Preliminary Study.Frontiers in psychology · 2021Article
- PKG1α oxidation negatively regulates food seeking behaviour and reward.Redox biology · 2019Article
- A narrative review of the construct of hedonic hunger and its measurement by the Power of Food Scale.Obesity science & practice · 2018Review
- Homeostatic modulation on unconscious hedonic responses to food.BMC research notes · 2017Article
- Weight Loss and Appetite Control in Women.Current obesity reports · 2017Review
- Subjective utility moderates bidirectional effects of conflicting motivations on pain perception.Scientific reports · 2017Article
- Central insulin modulates food valuation via mesolimbic pathways.Nature communications · 2017Article
- Feeding-modulatory effects of mu-opioids in the medial prefrontal cortex: a review of recent findings and comparison to opioid actions in the nucleus accumbens.Psychopharmacology · 2017Review
- Motivational state, reward value, and Pavlovian cues differentially affect skilled forelimb grasping in rats.Learning & memory (Cold Spring Harbor, N.Y.) · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe examined the impact of a 24 hour complete fast (vs. fed state) on two measures of food reward: 1) 'wanting', as measured by response to food images and by the relative-reinforcing value of food (RRV), and 2) 'liking', as measured by response to food images and the hedonic evaluation of foods consumed.
methodsUtilizing a randomized crossover design, 15 subjects (9 male; 6 female) aged 28.6±4.5 yrs with body mass index 25.3±1.4 kg/m(2) were randomized and counterbalanced to normal feeding (FED) and 24-hour fast (FASTED) conditions. Trait characteristics were measured with the Three Factor Eating Questionnaire. Two computer tasks measured food reward: 1) RRV progressive ratio task, 2) explicit 'liking' and 'wanting' (Leeds Food Preference Questionnaire, LFPQ). Also measured were ad libitum energy intake (EI; buffet) and food 'liking' (visual analogue scale) of personalized stimuli.
resultsThere were no significant anthropometric changes between conditions. Appetite scores, hedonic ratings of 'liking', and ad libitum EI all significantly increased under the FASTED condition (p<0.05). Under the FASTED condition there were significant increases in the RRV of snack foods; similarly, explicit 'wanting' and 'liking' significantly increased for all food categories. 'Liking' of sweet foods remained high across-meals under FASTED, but savory foods decreased in hedonic saliency.
conclusionRelative to a fed state, we observed an increase in hedonic ratings of food, the rewarding value of food, and food intake after a 24 hr fast. Alliesthesia to food and food cues is suggested by heightened hedonic ratings under the FASTED condition relative to FED.
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