Evidence map›Paper›PMID 24454841›Full record

ArticlePloS one2014

Food insecurity is associated with increased risk of non-adherence to antiretroviral therapy among HIV-infected adults in the Democratic Republic of Congo: a cross-sectional study.

Patou Masika Musumari, Edwin Wouters, Patrick Kalambayi Kayembe, Modeste Kiumbu Nzita, Samclide Mutindu Mbikayi, S Pilar Suguimoto, Teeranee Techasrivichien, Bhekumusa Wellington Lukhele, Christina El-Saaidi, Peter Piot and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02815579 (Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya), which is not on this map. Cited by 64 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02815579 nacompletednot on this mapstarted 2016, after this paper: background citation

Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya

TypeinterventionalSponsorUniversity of California, San FranciscoRan2016 to 2019Enrolled746ConditionsHIVArmsShamba Maisha Intervention
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  5. Journal of health care for the poor and underserved · 2018
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  14. Factors associated with non-adherence to antiretroviral therapy among adolescents in Oshikoto Region, Namibia.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Patou Masika MusumariDepartment of Global Health and Socio-epidemiology, Kyoto University School of Public Health, Kyoto, Japan.
Edwin WoutersDepartment of Sociology, Research Centre for Longitudinal and Life Course Studies, University of Antwerp, Antwerp, Belgium.
Patrick Kalambayi KayembeKinshasa University School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Modeste Kiumbu NzitaKinshasa University School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Samclide Mutindu MbikayiCentre Hospitalier Monkole, Kinshasa, Democratic Republic of Congo.
S Pilar SuguimotoDepartment of Global Health and Socio-epidemiology, Kyoto University School of Public Health, Kyoto, Japan.
Teeranee TechasrivichienDepartment of Global Health and Socio-epidemiology, Kyoto University School of Public Health, Kyoto, Japan.
Bhekumusa Wellington LukheleDepartment of Global Health and Socio-epidemiology, Kyoto University School of Public Health, Kyoto, Japan.
Christina El-SaaidiDepartment of Global Health and Socio-epidemiology, Kyoto University School of Public Health, Kyoto, Japan.
Peter PiotLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Masako Ono-KiharaDepartment of Global Health and Socio-epidemiology, Kyoto University School of Public Health, Kyoto, Japan.
Masahiro KiharaDepartment of Global Health and Socio-epidemiology, Kyoto University School of Public Health, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFood insecurity is increasingly reported as an important barrier of patient adherence to antiretroviral therapy (ART) in both resource-poor and rich settings. However, unlike in resource rich-settings, very few quantitative studies to date have investigated the association of food insecurity with patient adherence to ART in Sub-Saharan Africa. The current study examines the association between food insecurity and adherence to ART among HIV-infected adults in the Democratic Republic of Congo (DRC). METHODS AND

findingsThis is a cross-sectional quantitative study of patients receiving ART at three private and one public health facilities in Kinshasa, DRC. Participants were consecutively recruited into the study between April and November 2012. Adherence was measured using a combined method coupling pharmacy refill and self-reported adherence. Food insecurity was the primary predictor, and was assessed using the Household Food Insecurity Access Scale (HFIAS). Of the 898 participants recruited into the study, 512 (57%) were food insecure, and 188 (20.9%) were not adherent to ART. Food insecurity was significantly associated with non-adherence to ART (AOR, 2.06; CI, 1.38-3.09). We also found that perceived harmfulness of ART and psychological distress were associated respectively with increased (AOR, 1.95; CI, 1.15-3.32) and decreased (AOR, 0.31; CI, 0.11-0.83) odds of non-adherence to ART.

conclusionFood insecurity is prevalent and a significant risk factor for non-adherence to ART among HIV-infected individuals in the DRC. Our findings highlight the urgent need for strategies to improve food access among HIV-infected on ART in order to ensure patient adherence to ART and ultimately the long-term success of HIV treatment in Sub-Saharan Africa.

Indexed as

Food SupplyPatient ComplianceAdultAnti-HIV AgentsCross-Sectional StudiesDemocratic Republic of the CongoFemaleHIV InfectionsHumansMaleAnti-HIV Agents

Identifiers

PMID24454841
PMCPMC3893174

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.