ArticleJournal of breast cancer2013
Reliability of sentinel lymph node biopsy after neoadjuvant chemotherapy in breast cancer patients.
Article in Journal of breast cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Outcomes of Sentinel Node Biopsy for Women with Breast Cancer After Neoadjuvant Therapy: Systematic Review and Meta-Analysis of Real-World Data.Annals of surgical oncology · 2022Pooled it
- Sentinel lymph node mapping in breast cancer patients following neoadjuvant chemotherapy: systematic review and meta-analysis about head to head comparison of cN0 and cN + patients.Breast cancer (Tokyo, Japan) · 2022Pooled it
- Estimation of Hand Function Impairment in Breast Cancer Survivors with Lymphedema.South Asian journal of cancer · 2025Article
- The Feasibility and Reliability of Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Breast Cancer Patients With Negative Axillary Lymph Nodes-A Meta-analysis.Breast cancer : basic and clinical research · 2024Review
- Article
- Allicin induces cell cycle arrest and apoptosis of breast cancer cells in vitro via modulating the p53 pathway.Molecular biology reports · 2021Article
- Targeted axillary biopsy and sentinel lymph node biopsy for axillary restaging after neoadjuvant chemotherapy.Annals of surgical treatment and research · 2021Article
- Development and validation of a nomogram for prediction of lymph node metastasis in early-stage breast cancer.Gland surgery · 2021Article
- Association between Number of Retrieved Sentinel Lymph Nodes and Breast Cancer-related Lymphedema.Journal of breast cancer · 2021Article
- Article
- Minimal Invasive and Individualizing Management of the Axillary Nodes.Advances in experimental medicine and biology · 2021Article
- Assessment of sentinel lymph node biopsy after neoadjuvant chemotherapy for breast cancer in two subgroups: Initially node negative and node positive converted to node negative - A systemic review and meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019Review
- Can We Skip Intraoperative Evaluation of Sentinel Lymph Nodes? Nomogram Predicting Involvement of Three or More Axillary Lymph Nodes before Breast Cancer Surgery.Cancer research and treatment · 2017Article
- Development of a Nomogram to Predict N2 or N3 Stage in T1-2 Invasive Breast Cancer Patients with No Palpable Lymphadenopathy.Journal of breast cancer · 2017Article
- Sentinel lymph nodes for breast carcinoma: an update on current practice.Histopathology · 2016Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSentinel lymph node biopsy (SLNB) is an accurate and effective means of axillary nodal staging in early breast cancer. However its indication after neoadjuvant chemotherapy (NAC) is under constant debate. The present study evaluates the reliability of SLNB in assessing axillary nodal status after NAC.
methodsData from 281 patients who had received NAC and subsequent SLNB were reviewed. The identification and false negative rates of SLNB were determined and the clinicopathologic factors associated with false negative results were investigated using univariate analysis.
resultsThe identification rate of SLNB after NAC was 93.6% and the false negative rate was 10.4%. Hormone receptor status, especially progesterone receptor positivity, was significantly associated with false negative results. The accuracy of intraoperative frozen section examination of sentinel lymph nodes was 91.2%.
conclusionThe identification rate of SLNB and the accuracy of intraoperative frozen section examination after NAC are comparable to the results without NAC in patients with early breast cancer. However considering the high false negative rates, general application of SLNB after NAC should be avoided. Patients with progesterone-positive tumors and non-triple-negative breast cancers may be a select group of patients in whom SLNB can be employed safely after NAC, but further studies are necessary.
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