Evidence map›Paper›PMID 24453895›Full record

Trial reportTheScientificWorldJournal2013

Impact of sleep respiratory disorders on endothelial function in children.

Luigia Brunetti, Ruggiero Francavilla, Pietro Scicchitano, Valentina Tranchino, Maria Loscialpo, Michele Gesualdo, Annapaola Zito, Fara Fornarelli, Marco Sassara, Paola Giordano and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in TheScientificWorldJournal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. The predictive value of polysomnography combined with quality of life for treatment decision of children with habitual snoring related to adenotonsillar hypertrophy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Article
  6. Total analysis of clinical factors for surgical success of adenotonsillectomy in pediatric OSAS.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017
    Article
  7. The correlation between red blood cell distribution width levels with the severity of obstructive sleep apnea and carotid intima media thickness.Medical science monitor : international medical journal of experimental and clinical research · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Luigia BrunettiDepartment of Biomedicine of the Developmental Age, Pediatric Unit "S. Maggiore", University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Ruggiero FrancavillaDepartment of Biomedicine of the Developmental Age, Pediatric Unit "S. Maggiore", University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Pietro ScicchitanoCardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO), University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Valentina TranchinoDepartment of Biomedicine of the Developmental Age, Pediatric Unit "S. Maggiore", University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Maria LoscialpoDepartment of Biomedicine of the Developmental Age, Pediatric Unit "S. Maggiore", University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Michele GesualdoCardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO), University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Annapaola ZitoCardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO), University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Fara FornarelliCardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO), University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Marco SassaraCardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO), University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Paola GiordanoDepartment of Biomedicine of the Developmental Age, Pediatric Unit "S. Maggiore", University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Vito Leonardo MinielloDepartment of Biomedicine of the Developmental Age, Pediatric Unit "S. Maggiore", University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.
Marco Matteo CicconeCardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO), University of Bari, Piazza G. Cesare 11, 70124 Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea syndrome (OSAS) in children can induce endothelial dysfunction, a well-known early marker of atherosclerosis. The study aimed to evaluate a link among endothelial function (measured by flow-mediated vasodilation (FMD)), obesity (evaluated by body mass index (BMI)), and sleep disordered breathing (SDB), assessed with apnoea/hypopnoea index (AHI), in a paediatric population. We demonstrated that our little OSAS patients showed an impaired endothelial function as compared to controls. In particular, the higher the AHI, the worst the FMD values and thus the endothelial function. Although the population sample is small, this study demonstrated that OSAS could impair endothelial function and worsen cardiovascular risk profile since childhood.

Indexed as

VasodilationBlood Flow VelocityBrachial ArteryChildEndothelium, VascularFemaleHumansMaleReproducibility of ResultsSensitivity and SpecificitySleep Apnea Syndromes

Identifiers

PMID24453895
PMCPMC3888735

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.