ArticleTheScientificWorldJournal2013
Scientific validation of the medicinal efficacy of Tinospora cordifolia.
Article in TheScientificWorldJournal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dietary Polyphenols-Important Non-Nutrients in the Prevention of Chronic Noncommunicable Diseases. A Systematic Review.Nutrients · 2019Pooled it
- Green Synthesis and Characterization of Silver Nanoparticles fromNanomaterials (Basel, Switzerland) · 2025Article
- Immunomodulatory properties of Giloy (Heliyon · 2025Review
- Antioxidant, Alpha-Amylase Inhibitory and Hypoglycemic Activity ofFood science & nutrition · 2025Article
- Genotypes ofLife (Basel, Switzerland) · 2024Article
- Overview of Phytochemical Composition ofFoods (Basel, Switzerland) · 2024Review
- Proteomic Analysis of HepG2 Cells Reveals FAT10 and BAG2 Signaling Pathways Affected by a Protease Inhibitor fromTurkish journal of pharmaceutical sciences · 2024Article
- Review
- Elucidating the chemical profile and biological studies ofFrontiers in pharmacology · 2024Article
- The Antibacterial Effect of Tinospora Cordifolia (Guduchi) and Its Role in Combating Antimicrobial Resistance.Medeniyet medical journal · 2023Article
- Plant Polyphenols and Their Potential Benefits on Cardiovascular Health: A Review.Molecules (Basel, Switzerland) · 2023Review
- Two New Compounds from Allii Macrostemonis Bulbus and Their In Vitro Antioxidant Activities.Molecules (Basel, Switzerland) · 2023Article
- Phytochemical Composition, Antioxidant, Antibacterial, and Enzyme Inhibitory Activities of Various Organic Extracts fromPlants (Basel, Switzerland) · 2022Article
- Acute Sleep Deprivation-Induced Anxiety and Disruption of Hypothalamic Cell Survival and Plasticity: A Mechanistic Study of Protection by Butanol Extract of Tinospora cordifolia.Neurochemical research · 2022Article
- Origin and Function of Structural Diversity in the Plant Specialized Metabolome.Plants (Basel, Switzerland) · 2021Review
- Chemopreventive Role of Black Tea Extract in Swiss Albino Mice Exposed to Inorganic Arsenic.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- Polyphenols Targeting MAPK Mediated Oxidative Stress and Inflammation in Rheumatoid Arthritis.Molecules (Basel, Switzerland) · 2021Review
- A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov.Molecules (Basel, Switzerland) · 2021Review
- Antioxidant Activity and Healthy Benefits of Natural Pigments in Fruits: A Review.International journal of molecular sciences · 2021Review
- Grape polyphenols supplementation for exercise-induced oxidative stress.Journal of the International Society of Sports Nutrition · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Present communication reports the scientific evaluation of Tinospora cordifolia for its medicinal efficacy which includes phytochemical screening, antimicrobial, antioxidant, and anticancer activities of the plant. Secondary metabolites including anthraquinones, terpenoids, and saponins were present in many extracts in addition to phenolics. Total phenol contents in various extracts were found in the range of 8.75-52.50 catechol equivalent per gram (CE/g). In disc diffusion assays, polar extracts exhibited considerable inhibition against Klebsiella pneumoniae. Several other extracts also showed antibacterial activity against pathogenic strains of E. coli, Pseudomonas spp., and Proteus spp. Minimum bactericidal concentration (MBC) values of potential extracts were found between 1.29 and 22.73 mg/mL. The lowest MBC (1.29 mg/mL) was recorded for acetone and ethyl acetate extracts against K. pneumoniae and Pseudomonas spp., respectively. The antioxidant activity of the extracts was comparable to that of standard antioxidants and concentration-dependent response was shown in reducing power assay. Aqueous extracts demonstrated substantial metal ion chelating activity (67-95%) at lower concentrations (10-40 μ g/mL). Other extracts also exhibited considerable metal chelating response. Most of the extracts revealed considerable inhibition of MCF-7 cancer cell line. The study established remarkable antibacterial, antioxidant, and anticancer potential in T. cordifolia stem extracts.
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Registered trials
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