ArticleJournal of international oral health : JIOH2013
Annexin v - affinity assay - apoptosis detection system in granular cell ameloblastoma.
Article in Journal of international oral health : JIOH, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
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- Nanotechnology Based Repositioning of an Anti-Viral Drug for Non-Small Cell Lung Cancer (NSCLC).Pharmaceutical research · 2020Article
- Aggressive granular cell ameloblastoma: Report of a rare case.Journal of pharmacy & bioallied sciences · 2015Article
- Antigenic heterogeneity in granular cell ameloblastoma: an immunohistochemical study.Journal of international oral health : JIOH · 2015Article
- Granular cells in ameloblastoma: An enigma in diagnosis.Indian journal of dentistryArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the study is to detect apoptosis in granular cell ameloblastoma by annexin v affinity assay, a novel technique. MATERIALS &
methodsExcitional biopsy of two patients with granular cell ameloblastoma were fixed in buffered formalin and later embedded in paraffin wax. Blocks were sliced into 3m thick sections for routine histological and subsequent immunohistochemical examinations. For electron microscopic examination tissues were fixed in 2.5% glutaraldehyde.electron microscopic examination was carried out to find the nature of granularity in granular cell ameloblastoma which was finally confirmed by annexin v technique.
resultsAnnexin v is a sensitive marker to detect early apoptosis. Fluorescence in granular cell clusters showed that apoptotic cell death is higher in granular cells. Both early and late events of apoptosis were identified in annexin v staining and electron microscopic study respectively.
conclusionOur study confirms that increased apoptotic cell death and subsequent phagocytosis is responsible for granular appearance of cells in granular cell ameloblastoma compared with that of conventional ameloblastoma. How to cite this article: Balaji N, Devy AS, Sumathi MK, Vidyalakshmi S, Kumar GS, D'Silva S. Annexin V - Affinity Assay - Apoptosis Detection System in Granular Cell Ameloblastoma. J Int Oral Health 2013; 5(6):25-30 .
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Identifiers
24453441PMC3895714W2272982276What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.