Evidence map›Paper›PMID 24453392›Full record

ArticleIranian journal of medical sciences2014

In Vitro Antibacterial Activity of Several Plant Extracts and Oils against Some Gram-Negative Bacteria.

Ayman Al-Mariri, Mazen Safi

Abstract read
In one paragraph

Article in Iranian journal of medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Therapeutic Potential ofPlants (Basel, Switzerland) · 2025
    Article
  3. Fermented purple onion (Open veterinary journal · 2025
    Review
  4. The GenusCardiovascular & hematological agents in medicinal chemistry · 2025
    Review
  5. Article
  6. Impact ofVeterinary sciences · 2024
    Article
  7. Antibacterial and Antifungal Activities ofFoods (Basel, Switzerland) · 2024
    Article
  8. Postharvest Quality ofFoods (Basel, Switzerland) · 2024
    Article
  9. An Insight intoPlants (Basel, Switzerland) · 2023
    Review
  10. Life (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Article
  13. Antimicrobial Activity of Biogenic Silver Nanoparticles fromAntibiotics (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ayman Al-MaririDepartment of Molecular Biology and Biotechnology, Atomic Energy Commission, Damascus Syria.
Mazen SafiDepartment of Molecular Biology and Biotechnology, Atomic Energy Commission, Damascus Syria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedicinal plants are considered new resources for producing agents that could act as alternatives to antibiotics in the treatment of antibiotic-resistant bacteria. The aim of this study was to evaluate the antibacterial activity of 28 plant extracts and oils against four Gram-negative bacterial species.

methodsExperimental, in vitro, evaluation of the activities of 28 plant extracts and oils as well as some antibiotics against E. coli O157:H7, Yersinia enterocolitica O9, Proteus spp., and Klebsiella pneumoniae was performed. The activity against 15 isolates of each bacterium was determined by disc diffusion method at a concentration of 5%. Microdilution susceptibility assay was used in order to determine the minimal inhibitory concentrations (MICs) of the plant extracts, oils, and antibiotics.

resultsAmong the evaluated herbs, only Origanum syriacum L., Thymus syriacus Boiss., Syzygium aromaticum L., Juniperus foetidissima Wild, Allium sativum L., Myristica fragrans Houtt, and Cinnamomum zeylanicum L. essential oils and Laurus nobilis L. plant extract showed anti-bacterial activity. The MIC50 values of these products against the Gram-negative organisms varied from 1.5 (Proteus spp. and K. pneumoniae( and 6.25 µl/ml (Yersinia enterocolitica O9 ) to 12.5 µl/ml (E. coli O:157).

conclusionAmong the studied essential oils, O. syriacum L., T. syriacus Boiss., C. zeylanicum L., and S. aromaticum L. essential oils were the most effective. Moreover, Cephalosporin and Ciprofloxacin were the most effective antibiotics against almost all the studied bacteria. Therefore, O. syriacum L., T. syriacus Boiss., C. zeylanicum L., and S. aromaticum L. could act as bactericidal agents against Gram-negative bacteria.

Indexed as

Antibiotic resistanceCinnamomum zeylanicumGram-negative bacteriaSyzygium aromaticum

Identifiers

PMID24453392
PMCPMC3895893

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.