ArticleJournal of neurophysiology2014
Reorganization of muscle synergies during multidirectional reaching in the horizontal plane with experimental muscle pain.
Article in Journal of neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Motor Learning in Response to Different Experimental Pain Models Among Healthy Individuals: A Systematic Review.Frontiers in human neuroscience · 2022Pooled it
- The influence of musculoskeletal pain disorders on muscle synergies-A systematic review.PloS one · 2018Pooled it
- The effect of experimentally induced acute pain on lumbar movement control: a single blinded three-arm cross-over randomized control trial.BMC musculoskeletal disorders · 2026Trial
- Acute pain impairs retention of locomotor learning.Journal of neurophysiology · 2024Trial
- Projecting the new body: How body image evolves during learning to walk with a wearable robot.PNAS nexus · 2026Article
- Machine learning analysis of surface electromyography for quantifying neuromuscular compensatory profiles and associated functional disability in neck pain.Frontiers in bioengineering and biotechnology · 2026Article
- Electro-tactile modulation of muscle activation and intermuscular coordination in the human upper extremity.Scientific reports · 2025Article
- Stretchable surface electromyography electrode array patch for tendon location and muscle injury prevention.Nature communications · 2023Article
- Muscle synergy patterns as altered coordination strategies in individuals with chronic low back pain: a cross-sectional study.Journal of neuroengineering and rehabilitation · 2023Article
- Muscle synergies for evaluating upper limb in clinical applications: A systematic review.Heliyon · 2023Review
- Differences in Trapezius Muscle H-Reflex between Asymptomatic Subjects and Symptomatic Shoulder Pain Subjects.Sensors (Basel, Switzerland) · 2023Article
- Variability of trunk muscle synergies underlying the multidirectional movements and stability trunk motor tasks in healthy individuals.Scientific reports · 2023Article
- Generalizability of muscle synergies in isometric force generation versus point-to-point reaching in the human upper extremity workspace.Frontiers in human neuroscience · 2023Article
- Optimal Identification of Muscle Synergies From Typical Sit-to-Stand Clinical Tests.IEEE open journal of engineering in medicine and biology · 2023Article
- Neck Pain: Do We Know Enough About the Sensorimotor Control System?Frontiers in computational neuroscience · 2022Review
- Paraspinal strength and electromyographic fatigue in patients with sub-acute back pain and controls: Reliability, clinical applicability and between-group differences.World journal of orthopedics · 2021Article
- How to improve the muscle synergy analysis methodology?European journal of applied physiology · 2021Review
- Article
- Shoulder muscle activation strategies differ when lifting or lowering a load.European journal of applied physiology · 2020Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Muscle pain induces a complex reorganization of the motor strategy which cannot be fully explained by current theories. We tested the hypothesis that the neural control of muscles during reaching in the presence of nociceptive input is determined by a reorganization of muscle synergies with respect to control conditions. Muscle pain was induced by injection of hypertonic saline into the anterior deltoid muscle of eight men. Electromyographic (EMG) signals were recorded from 12 upper limb muscles as subjects performed a reaching task before (baseline) and after the injection of hypertonic (pain) saline, and after the pain sensation vanished. The EMG envelopes were factorized in muscle synergies, and activation signals extracted for each condition. Nociceptive stimulation resulted in a complex muscle reorganization without changes in the kinematic output. The anterior deltoid muscle activity decreased in all subjects while the changes in other muscles were subject specific. Three synergies sufficed to describe the EMG patterns in each condition, suggesting that reaching movements remain modular in the presence of experimental pain. Muscle reorganization in all subjects was accompanied by a change in the activation signals compatible with a change in the central drive to muscles. One, two or three synergies were shared between the baseline and painful conditions, depending on the subject. These results indicate that nociceptive stimulation may induce a reorganization of modular control in reaching. We speculate that such reorganization may be due to the recruitment of synergies specific to the painful condition.
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