SynthesisClinical oral investigations2014
Mineral trioxide aggregate versus formocresol pulpotomy: a systematic review and meta-analysis of randomized clinical trials.
Synthesis in Clinical oral investigations, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Mapping Systematic Reviews on the Management of Dental Caries in Primary Teeth: A Meta-research.Current pediatric reviews · 2026Pooled it
- MTA and biodentine for primary teeth pulpotomy: a systematic review and meta-analysis of clinical trials.Clinical oral investigations · 2019Pooled it
- Pulp treatment for extensive decay in primary teeth.The Cochrane database of systematic reviews · 2018Pooled it
- Evidence of pulpotomy in primary teeth comparing MTA, calcium hydroxide, ferric sulphate, and electrosurgery with formocresol.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2015Pooled it
- Clinical and radiographic outcomes of four pulpotomy agents in primary molars: a prospective randomized controlled trial.Odontology · 2026Trial
- Clinical and radiographic comparison of primary molar pulpotomy using formocresol, portland cement, and NeoMTA plus: a randomized controlled clinical trial.Scientific reports · 2024Trial
- Success Rates of Pulpotomies in Primary Molars Using Calcium Silicate-Based Materials: A Randomized Control Trial.BioMed research international · 2017Trial
- Short-term treatment outcome of pulpotomies in primary molars using mineral trioxide aggregate and Biodentine: a randomized clinical trial.Clinical oral investigations · 2016Trial
- Clinical decision-making in pulp therapy of primary teeth among Tunisian dental practitioners: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Outcomes and predictive factors of vital pulp therapy in a large-scale retrospective cohort study over 10 years.Scientific reports · 2024Article
- A Randomized Controlled Clinical Trial Comparing Clinical and Radiographic Success Rates of MTA and rhBMP2 in Pulpotomy of Primary Teeth.Frontiers in dentistry · 2024Article
- Does the use of natural products for endodontic therapy in primary teeth have sufficient evidence for clinical practice? A scoping review.Clinical oral investigations · 2022Article
- Evaluation of the Shear Bond Strength of Four Bioceramic Materials with Different Restorative Materials and Timings.Materials (Basel, Switzerland) · 2022Article
- Article
- Vital and Nonvital Pulp Therapy in Primary Dentition: An Umbrella Review.Journal of clinical medicine · 2021Review
- Prognostic factors for the survival of primary molars following pulpotomy with mineral trioxide aggregate: a retrospective cohort study.Clinical oral investigations · 2021Article
- Mineral Trioxide Aggregate and Diluted Formocresol Pulpotomy: Prospective and Retrospective Study Outcomes.The Journal of the Michigan Dental Association · 2018Article
- Evaluation of Four Pulpotomy Techniques in Primary Molars: A Randomized Controlled Trial.Iranian endodontic journal · 2018Article
- Postoperative Pain following Pulpotomy of Primary Molars with Two Biomaterials: A Randomized Split Mouth Clinical Trial.Iranian endodontic journal · 2017Article
- A review on vital pulp therapy in primary teeth.Iranian endodontic journal · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study systematically reviewed randomized clinical trials (RCTs) investigating the effectiveness of primary molar pulpotomies with mineral trioxide aggregate (MTA) and formocresol. The study also aimed to assess the possible association of reported prognostic factors on the success rate and relative risk using meta-regression analysis. MATERIALS AND
methodsA comprehensive literature search using Medline, EMBASE, and Cochrane Central databases up to March 2013 was conducted. After scoring and data extraction of qualified trials (n = 19, representing 1,585 patients), meta-analyses were performed using Mantel-Haenszel model and inverse variance-weighted method.
resultsThe results revealed that MTA is more effective than formocresol in primary molars pulpotomy, resulting in a lower failure rate with a relative risk of 0.26 (CI, 0.13-0.49), 0.37 (CI, 0.19-0.70), and 0.41 (CI, 0.25-0.68) for 6-, 12-, and 24-month follow-ups (test for statistical heterogeneity: p = 0.99, p = 0.98, and p = 0.23), respectively. Compared to amalgam restoration, success rate was significantly greater with SS crown (P < 0.05); however, no evidence for association between other reported prognostic factors such as selection of first/second molar, upper/lower jaw, gender, and various follow-up times with treatment success was observed.
conclusionsBased on the quality, homogeneity, and sufficient number of included RCTs, primary molar pulpotomy with MTA can produce a higher success rate in comparison with formocresol. CLINICAL RELEVANCE: When compared with formocresol, MTA pulpotomy is superior in treating primary molars.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.