Evidence map›Paper›PMID 24452733›Full record

ArticleInternational journal of STD & AIDS2014

Correlates of syphilis seropositivity and risk for syphilis-associated adverse pregnancy outcomes among women attending antenatal care clinics in the Democratic Republic of Congo.

Melanie M Taylor, Shahul Ebrahim, Nadine Abiola, Didine Kaba Kinkodi, Minlangu Mpingulu, Jean Pierre Kabuayi, Felly Ekofo, Daniel R Newman, Thomas A Peterman, Mary L Kamb and 1 more

Abstract read
In one paragraph

Article in International journal of STD & AIDS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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  9. The magnitude of syphilis: from prevalence to vertical transmission.Revista do Instituto de Medicina Tropical de Sao Paulo · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Melanie M TaylorCenters for Disease Control and Prevention, Division of STD Prevention, Atlanta, GA, USA MDT7@CDC.GOV.
Shahul EbrahimCenters for Disease Control and Prevention, Global AIDS Program, Kinshasa, DRC.
Nadine AbiolaCenters for Disease Control and Prevention, Global AIDS Program, Kinshasa, DRC.
Didine Kaba KinkodiKinshasa School of Public Health, Kinshasa, DRC.
Minlangu MpinguluCenters for Disease Control and Prevention, Global AIDS Program, Kinshasa, DRC.
Jean Pierre KabuayiMinistère de la Santé Publique, Program National de Lutte Contre le VIH/SIDA, Kinshasa, DRC.
Felly EkofoMinistère de la Santé Publique, Program National de Lutte Contre le VIH/SIDA, Kinshasa, DRC.
Daniel R NewmanCenters for Disease Control and Prevention, Division of STD Prevention, Atlanta, GA, USA.
Thomas A PetermanCenters for Disease Control and Prevention, Division of STD Prevention, Atlanta, GA, USA.
Mary L KambCenters for Disease Control and Prevention, Division of STD Prevention, Atlanta, GA, USA.
Kassim SidibeCenters for Disease Control and Prevention, Global AIDS Program, Kinshasa, DRC.
Centers for Disease Control and Prevention · USCenters for Disease Control and Prevention · UGMinistry of Public Health · CD

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Screening and treatment for syphilis among pregnant women is the primary means of prevention of congenital syphilis. Sentinel surveillance for syphilis can inform these prevention efforts. We reviewed antenatal syphilis screening results to assess trends and to identify correlates of seropositivity among women attending antenatal care clinics in the Democratic Republic of Congo during 2011. Syphilis seropositivity among the 17,669 women attending the antenatal care clinics during 2011 was 4.2% (range 0.4%-16.9%). Syphilis seropositivity was significantly higher among women attending rural clinics (5.0%) as compared to urban clinics (3.0%) and those tested in antenatal care clinics in the provinces of Equateur (7.6%) and Orientale (7.7%) as compared to other provinces (p < 0.001). Based on the antenatal care syphilis seroprevalence and national pregnancy estimates, we estimate that approximately 128,591 pregnant women countrywide would have tested seropositive for syphilis during 2011. Over 85,000 adverse pregnancy outcomes would have resulted from these maternal infections, assuming prenatal syphilis diagnosis and treatment were not available. The prevalence of syphilis was highest in rural areas, but exceeded 1% in every area, indicating a need to assure screening and treatment throughout Democratic Republic of Congo. These sentinel surveillance estimates can be used to guide national congenital syphilis prevention efforts.

Indexed as

Pregnancy OutcomeAdolescentAdultDemocratic Republic of the CongoFemaleHumansInfectious Disease Transmission, VerticalMass ScreeningMiddle AgedPregnancyPregnancy Complications, ParasiticPrenatal CarePrevalenceRisk FactorsRural PopulationSentinel Surveillanceantenatal carecongenital syphilisDemocratic Republic of CongopreventionscreeningseroprevalenceSTDSTISyphilis

Identifiers

PMID24452733
PMCPMC6764440
OpenAlexW2119050035

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.