SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2014
Cause and outcome of cerebellar mutism: evidence from a systematic review.
Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Cerebellar mutism syndrome caused by bilateral cerebellar hemorrhage in adults: a case report and review of the literature.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Pooled it
- The Cerebellar Cognitive Affective Syndrome-a Meta-analysis.Cerebellum (London, England) · 2019Pooled it
- Trial
- Preoperative hydrocephalus and the risk of postoperative speech impairment following posterior fossa tumour surgery in children: results from a prospective, multinational cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Observational
- Risk factors associated with cerebellar mutism syndrome and late postoperative hydrocephalus following pediatric posterior fossa medulloblastoma surgery.Frontiers in oncology · 2026Article
- Article
- The Cerebellar Mutism Syndrome: Risk Assessment, Prevention and Treatment.Advances and technical standards in neurosurgery · 2023Article
- Posterior fossa syndrome in a population of children and young adults with medulloblastoma: a retrospective, multicenter Italian study on incidence and pathophysiology in a histologically homogeneous and consecutive series of 136 patients.Journal of neuro-oncology · 2022Article
- Postoperative speech impairment and cranial nerve deficits after secondary surgery of posterior fossa tumours in childhood: a prospective European multicentre study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Cognitive, language, and school performance in children and young adults treated for low-grade astrocytoma in the posterior fossa in childhood.Cancer reports (Hoboken, N.J.) · 2022Article
- The medical therapy for cerebellar mutism syndrome: a case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Review
- Preoperative prediction of postoperative cerebellar mutism syndrome. Validation of existing MRI models and proposal of the new Rotterdam pCMS prediction model.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- The supplementary motor area syndrome and the cerebellar mutism syndrome: a pathoanatomical relationship?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Review
- Conversations on mutism: risk stratification for cerebellar mutism based on medulloblastoma subtype.Neuro-oncology · 2020Article
- Neuropsychological Profile in Children with Posterior Fossa Tumors with or Without Postoperative Cerebellar Mutism Syndrome (CMS).Cerebellum (London, England) · 2020Article
- Mutism resulting from heterochronic bilateral cerebellar hemorrhages - A case report.Surgical neurology international · 2019Article
- [Selective mutism].Der Nervenarzt · 2018Article
- Hypertrophic olivary degeneration in children after posterior fossa surgery. An underdiagnosed condition.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Review
- Analysis of surgical and MRI factors associated with cerebellar mutism.Journal of neuro-oncology · 2017Article
- Posterior fossa syndrome-a narrative review.Quantitative imaging in medicine and surgery · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCerebellar mutism is a serious neurosurgical complication after posterior fossa surgery, but the cause, incidence and outcome remain incompletely defined. The aim of this paper was to identify and review all reports of this phenomenon to better delineate and improve the evidence base.
methodsA systematic search and retrieval of databases was conducted using advanced search techniques. Review/outcomes criteria were developed, and study quality was determined.
resultsThe retrieval identified 2,281 papers of which 96 were relevant, identifying 650 children with cerebellar mutism. Causative factors, clinical features and outcomes were reported variably; papers focussed on multiple areas, the majority reporting incidence in single or series of case studies with little or no analysis further than description.
conclusionsThe complexity and variability of data reporting, likely contributing factors and outcomes make cerebellar mutism difficult to predict in incidence and the degree of impact that may ensue. A clear and accepted universal definition would help improve reporting, as would the application of agreed outcome measures. Clear and consistent reporting of surgical technique remains absent. Recommendations for practice are provided.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.