Evidence map›Paper›PMID 24452255›Full record

ArticleInternational journal of environmental research and public health2013

Toxic metal concentrations in cigarettes obtained from U.S. smokers in 2009: results from the International Tobacco Control (ITC) United States survey cohort.

Rosalie V Caruso, Richard J O'Connor, W Edryd Stephens, K Michael Cummings, Geoffrey T Fong

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. A Comparative Health Risk Assessment of Electronic Cigarettes and Conventional Cigarettes.International journal of environmental research and public health · 2017
    Pooled it
  2. Pooled it
  3. Trial
  4. Demographic Factors Affect the BMAC Proteome.Journal of proteome research · 2026
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  10. Profibrotic predictive toxicology in the lung.Frontiers in pharmacology · 2026
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Rosalie V CarusoDepartment of Health Behavior, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA. Rosalie.Caruso@RoswellPark.org.
Richard J O'ConnorDepartment of Health Behavior, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA. richard.oconnor@roswellpark.org.
W Edryd StephensDepartment of Earth & Environmental Sciences, University of St Andrews, Irvine Building, North Street, St Andrews, Fife, KY16 9AL, UK. wes@st-andrews.ac.uk.
K Michael CummingsDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA. cummingk@musc.edu.
Geoffrey T FongDepartment of Psychology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada. geoffrey.fong@uwaterloo.ca.
Roswell Park Comprehensive Cancer Center · USMedical University of South Carolina · USUniversity of St Andrews · GBUniversity of Waterloo · CA

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI CANDACE S JOHNSON · 1985 to 2026
$116.6M
Variation in Cigarettes, Tobacco use Behaviors and Exposures in ITC CountriesP01CA138389 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI FONG, GEOFFREY T · 2009 to 2013
$13.4M
International Tobacco Policy SurveyR01CA100362 · NCI · UNIVERSITY OF WATERLOO · PI FONG, GEOFFREY T · 2005 to 2013
$4.7M
CIHRNCI NIH HHS P01 CA138389NCI NIH HHS P30 CA016056NCI NIH HHS R01 CA100362
6 · The paper itself

Abstract

Smoking-related diseases can be attributed to the inhalation of many different toxins, including heavy metals, which have a host of detrimental health effects. The current study reports the levels of arsenic (As), cadmium (Cd), chromium (Cr), nickel (Ni), and lead (Pb) in cigarettes obtained from adult smokers participating in the 2009 wave of the ITC United States Survey (N = 320). The mean As, Cd, Cr, Ni, and Pb levels were 0.17, 0.86, 2.35, 2.21, and 0.44 µg/g, respectively. There were some differences in metal concentrations of cigarette brands produced by different manufacturers, suggesting differences in the source of tobaccos used by different companies. For Ni, there were significant pairwise differences between Philip Morris U.S. (PMUSA) and R.J. Reynolds (RJR) brands (PMUSA higher; p < 0.001), PMUSA and other manufacturer (OM) brands (PMUSA higher; p < 0.001), and RJR and OM brands (RJR higher; p = 0.006). For Cr, RJR brands had higher levels than did OM brands (p = 0.02). Levels of As, Cd, and Pb did not differ significantly across manufacturer groups (p > 0.10). Because of the variety of toxic heavy metals in cigarette tobacco, and their numerous negative health effects, metal content in cigarette tobacco should be reduced.

Indexed as

ArsenicHumansMetals, HeavyRegression AnalysisTobacco ProductsUnited StatesArsenicMetals, Heavy

Identifiers

PMID24452255
PMCPMC3924441
OpenAlexW2053305069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.