Trial reportJournal of clinical microbiology2014
Concordance of PCR and culture from nasal swabs for detection of methicillin-resistant Staphylococcus aureus in a setting of concurrent antistaphylococcal antibiotics.
Trial report in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01234831 (A Novel Approach to MRSA Screening of Colonized Patients and Impact on Hospital Resource Allocation and Patient Care), which is not on this map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Novel Approach to MRSA Screening of Colonized Patients and Impact on Hospital Resource Allocation and Patient Care
Who cites it
8 citing papers in PubMed.
- Evaluation of the Impact of Universal Mupirocin Decolonization in Intensive Care Units on the Utility of Methicillin-Resistant Staphylococcus aureus Polymerase Chain Reaction Nasal Swab Testing.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Culture harder: use more specimens to increase methicillin-resistant Staphylococcus aureus culture yield relative to PCR.Access microbiology · 2025Article
- Article
- Evaluation of methicillin-resistantAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- Pet animals as reservoirs for spreading methicillin-resistantJournal of advanced veterinary and animal research · 2023Article
- Utility of Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2021Article
- Impact of Nasal Swabs on Empiric Treatment of Respiratory Tract Infections (INSERT-RTI).Pharmacy (Basel, Switzerland) · 2020Article
- The role of Staphylococcus aureus carriage in the pathogenesis of bloodstream infection.BMC research notes · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The effect of concurrent administration of antibiotics on the detection of methicillin-resistant Staphylococcus aureus (MRSA) remains unresolved. Here, we assessed the concordance of paired nasal swabs processed using commercial PCR and culture and found high concordance in both the absence and presence of antibiotics with activity against MRSA (93.7% [95% confidence interval [CI], 88.1%, 96.8%] and 90.9% [95% CI, 84.8%, 94.7%], respectively), although PCR was more likely to be positive in the presence of antibiotics. (This study has been registered at ClinicalTrials.gov under registration no. NCT01234831.).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.