ReviewMedical science monitor : international medical journal of experimental and clinical research2014
Primary cardiac angiosarcoma - a review.
Review in Medical science monitor : international medical journal of experimental and clinical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
112 citing papers in PubMed, 1 synthesis or guideline pooled it, 194 citations in OpenAlex.
- Diagnostic test accuracies of F-18 FDG PET for characterisation of cardiac masses compared to conventional imaging techniques: systematic review and meta-analysis.The British journal of radiology · 2022Pooled it
- Stereotactic heart ablative radiotherapy (SHARP): a prospective multicentric phase II trial.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Trial
- Demographics and factors influencing mortality among cardiac angiosarcoma patients and genomic studies correlation for future personalized management.Proceedings (Baylor University. Medical Center) · 2026Article
- Primary cardiac angiosarcoma: From pathogenesis to therapeutic strategies.Medical oncology (Northwood, London, England) · 2026Review
- Late-Onset Familial Primary Cardiac Angiosarcoma in Two Sisters.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Primary Cardiac Angiosarcoma in a Young Male: Rare Presentation With Right Atrial Endocardial Dissection and Right Coronary Artery Tumor Fistula.Clinical case reports · 2026Article
- Primary Epithelioid Angiosarcoma of the Right Atrium Presenting With Symptomatic Bradycardia: A Case Report.Cureus · 2026Article
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- Primary cardiac angiosarcoma with isolated superior vena cava syndrome: a case report.Journal of medical case reports · 2026Article
- Primary Cardiac Synovial Sarcoma (PCSS): Clinicopathologic Features of 6 Cases and Literature Comparison.Cardiology research and practice · 2026Article
- Emergency Surgery for Left Atrial Angiosarcoma Presenting with Acute Respiratory Failure: A Fatal Case Report.Surgical case reports · 2026Article
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- The bleeding heart: A case of cardiac angiosarcoma presenting with pulmonary hemorrhage and hemoptysis.Radiology case reports · 2025Article
- Primary cardiac angiosarcoma - a diagnostic roller-coaster till fatality.Journal of cardiovascular and thoracic research · 2025Article
- Heart team rescues a bleeding heart: a case report of cardiac angiosarcoma causing life-threatening tamponade.European heart journal. Case reports · 2025Article
- Diagnosis and treatment of cardiac tumors.Medical oncology (Northwood, London, England) · 2025Review
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- Advancements in Diagnosis and Treatment of Cardiac Sarcomas: A Comprehensive Review.Current treatment options in oncology · 2025Review
52 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary cardiac neoplasms are extremely rare. Angiosarcoma is the most commonly seen histological subtype and is characterized by its permeating and destructive nature. Unfortunately, primary cardiac angiosarcoma is often overlooked as an initial diagnosis because of its rarity. Since the time it was first identified in 1934, little progress has been made in improving survival outcome. Complete or partial surgical resection is still the best option for palliation, with little hope for cure. Improvements have been made in the ability to view and distinguish tumors. Echocardiography is one of the most useful diagnostic tools because of its high sensitivity; therefore, CT and MR images are often used to detect sites of metastatic disease. Immunohistochemistry staining can also be employed as an adjunctive diagnostic tool. CD31, CD34, FLI-1, and von Willebrand factor are the most commonly used markers in detecting tumors of endothelial origin. However, due to the vast heterogeneity within a tumor, immunohistochemistry staining can be quite variable. Surgical resection remains the standard modality of treatment. Primary cardiac angiosarcoma is largely resistant to chemotherapy and/or radiation. However, the exact benefit and its place in a multimodality treatment regimen are still under investigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.