Evidence map›Paper›PMID 24451843›Full record

ReviewToxins2013

Deoxynivalenol: a major player in the multifaceted response of Fusarium to its environment.

Kris Audenaert, Adriaan Vanheule, Monica Höfte, Geert Haesaert

Abstract readReview
In one paragraph

Review in Toxins, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Biological control ofFrontiers in microbiology · 2026
    Article
  8. Article
  9. Ecophysiological behavior of majorApplied and environmental microbiology · 2025
    Article
  10. Article
  11. Article
  12. FGSE02, a Novel Secreted Protein inJournal of fungi (Basel, Switzerland) · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Real-Time COToxins · 2025
    Article
  17. Article
  18. The biocontrol agentFrontiers in plant science · 2025
    Article
  19. Molecular identification and pathogenic impact ofFrontiers in microbiology · 2025
    Article
  20. Review

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kris AudenaertDepartment of Applied BioSciences, Faculty Bioscience Engineering, Ghent University, Valentin Vaerwyckweg, 1, Ghent 9000, Belgium. kris.audenaert@ugent.be.
Adriaan VanheuleDepartment of Applied BioSciences, Faculty Bioscience Engineering, Ghent University, Valentin Vaerwyckweg, 1, Ghent 9000, Belgium. adriaan.vanheule@ugent.be.
Monica HöfteDepartment of Crop Protection, Laboratory of Phytopathology, Faculty Bioscience Engineering, Ghent University, Coupure links 653, Ghent 9000, Belgium. monica.hofte@ugent.be.
Geert HaesaertDepartment of Applied BioSciences, Faculty Bioscience Engineering, Ghent University, Valentin Vaerwyckweg, 1, Ghent 9000, Belgium. geert.haesaert@ugent.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mycotoxin deoxynivalenol (DON), produced by several Fusarium spp., acts as a virulence factor and is essential for symptom development after initial wheat infection. Accumulating evidence shows that the production of this secondary metabolite can be triggered by diverse environmental and cellular signals, implying that it might have additional roles during the life cycle of the fungus. Here, we review data that position DON in the saprophytic fitness of Fusarium, in defense and in the primary C and N metabolism of the plant and the fungus. We combine the available information in speculative models on the role of DON throughout the interaction with the host, providing working hypotheses that await experimental validation. We also highlight the possible impact of control measures in the field on DON production and summarize the influence of abiotic factors during processing and storage of food and feed matrices. Altogether, we can conclude that DON is a very important compound for Fusarium to cope with a changing environment and to assure its growth, survival, and production of toxic metabolites in diverse situations.

Indexed as

Animal FeedCarbohydrate MetabolismFood ContaminationFood MicrobiologyFood StorageFungicides, IndustrialFusariumNitrogenPlant DiseasesTrichothecenesTriticumdeoxynivalenolFungicides, IndustrialNitrogenTrichothecenes

Identifiers

PMID24451843
PMCPMC3920246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.