Evidence map›Paper›PMID 24451612›Full record

Trial reportJournal of occupational and environmental medicine2014

A naturopathic approach to the prevention of cardiovascular disease: cost-effectiveness analysis of a pragmatic multi-worksite randomized clinical trial.

Patricia M Herman, Orest Szczurko, Kieran Cooley, Dugald Seely

Registry-linked trialAbstract readPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Journal of occupational and environmental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT00718796. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00718796 phase3completed

Naturopathic Treatment for the Prevention of Cardiovascular Disease: a Pragmatic Randomized Controlled Trial

Ran2008Enrolled300Registered outcomes6Posted comparisons0ConditionsCardiovascular DiseaseArmsConventional medical treatment (Atorvastatin,Fluvastatin,Lovastatin,Pravastatin,Rosuvastatin,Simvastatin), Naturopathic medicine. May include: fish oil, plant sterols, soluble fiber, cinnamon, coQ10 and exercise
Open the trial in the graph
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Whole Systems Research Methods in Health Care: A Scoping Review.Journal of alternative and complementary medicine (New York, N.Y.) · 2019
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Patricia M HermanFrom the Center for Health Outcomes and Pharmacoeconomics Research (Dr Herman), University of Arizona, and the RAND Corporation, Santa Monica, Calif; Department of Research and Clinical Epidemiology (Drs Szczurko, Cooley, and Seely), Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada; and Department of Social and Administrative Pharmacy (Drs Szczurko and Cooley), University of Toronto, Toronto, Ontario, Canada.
Orest Szczurko
Kieran Cooley
Dugald Seely
Canadian College of Naturopathic Medicine · CA

Funding

Mechanisms of Radiation Induced Fatigue in CancerK07CA090407 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BOWER, JULIENNE E · 2001 to 2006
$636k
NCI NIH HHS K07 CA090407
6 · The paper itself

Abstract

objectiveTo determine the cost-effectiveness of a worksite-based naturopathic (individualized lifestyle counseling and nutritional medicine) approach to primary prevention of cardiovascular disease (CVD).

methodsEconomic evaluation alongside a pragmatic, multi-worksite, randomized controlled trial comparing enhanced usual care (EUC; usual care plus biometric screening) to the addition of a naturopathic approach to CVD prevention (NC+EUC).

resultsAfter 1 year, NC+EUC resulted in a net decrease of 3.3 (confidence interval: 1.7 to 4.8) percentage points in 10-year CVD event risk (number needed to treat = 30). These risk reductions came with average net study-year savings of $1138 in societal costs and $1187 in employer costs. There was no change in quality-adjusted life years across the study year.

conclusionsA naturopathic approach to CVD primary prevention significantly reduced CVD risk over usual care plus biometric screening and reduced costs to society and employers in this multi-worksite-based study. Trial Registration clinicaltrials.gov Identifier: NCT00718796.

Indexed as

AdultAgedCanadaCardiovascular DiseasesCost-Benefit AnalysisDiet TherapyDirective CounselingFemaleHealth Care CostsHealth PromotionHumansMaleMiddle AgedNaturopathyOccupational Health ServicesPrimary Prevention

Identifiers

PMID24451612
PMCPMC3921268
OpenAlexW2104445551

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.