Evidence map›Paper›PMID 24451310›Full record

ReviewNutrients2014

Recent advances and uses of grape flavonoids as nutraceuticals.

Vasil Georgiev, Anthony Ananga, Violeta Tsolova

Abstract readReview
In one paragraph

Review in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed.

  1. Trial
  2. Review
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  6. Article
  7. Review
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  9. Article
  10. Grape Marc as a Functional Feed Ingredient for Farmed SnailsAnimals : an open access journal from MDPI · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
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  18. Article
  19. Review
  20. Article

61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vasil GeorgievCenter for Viticulture and Small Fruit Research, College of Agriculture and Food Sciences, Florida A & M University, 6505 Mahan Drive, Tallahassee, FL 32317, USA. Vasil.Georgiev@famu.edu.
Anthony AnangaCenter for Viticulture and Small Fruit Research, College of Agriculture and Food Sciences, Florida A & M University, 6505 Mahan Drive, Tallahassee, FL 32317, USA. anthony.ananga@gmail.com.
Violeta TsolovaCenter for Viticulture and Small Fruit Research, College of Agriculture and Food Sciences, Florida A & M University, 6505 Mahan Drive, Tallahassee, FL 32317, USA. violetka.colova@famu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Grape is one of the oldest fruit crops domesticated by humans. The numerous uses of grape in making wine, beverages, jelly, and other products, has made it one of the most economically important plants worldwide. The complex phytochemistry of the berry is characterized by a wide variety of compounds, most of which have been demonstrated to have therapeutic or health promoting properties. Among them, flavonoids are the most abundant and widely studied, and have enjoyed greater attention among grape researchers in the last century. Recent studies have shown that the beneficial health effects promoted by consumption of grape and grape products are attributed to the unique mix of polyphenolic compounds. As the largest group of grape polyphenols, flavonoids are the main candidates considered to have biological properties, including but not limited to antioxidant, anti-inflammatory, anti-cancer, antimicrobial, antiviral, cardioprotective, neuroprotective, and hepatoprotective activities. Here, we discuss the recent scientific advances supporting the beneficial health qualities of grape and grape-derived products, mechanisms of their biological activity, bioavailability, and their uses as nutraceuticals. The advantages of modern plant cell based biotechnology as an alternative method for production of grape nutraceuticals and improvement of their health qualities are also discussed.

Indexed as

AbsorptionAnimalsAntioxidantsBeveragesBiological AvailabilityDietary SupplementsFlavonoidsFruitHumansModels, AnimalPlant CellsPlant ExtractsPolyphenolsSeedsVitisWineAntioxidantsFlavonoidsPlant ExtractsPolyphenols

Identifiers

PMID24451310
PMCPMC3916869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.