ArticleDevelopment (Cambridge, England)2014
Multiple developmental mechanisms regulate species-specific jaw size.
Article in Development (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Neural crest gene regulatory networks as drivers of development, diversification and disease.Nature reviews. Molecular cell biology · 2026Review
- Article
- Genetic and Developmental Divergence in the Neural Crest Program between Cichlid Fish Species.Molecular biology and evolution · 2024Article
- Cellular, Molecular, and Genetic Mechanisms of Avian Beak Development and Evolution.Annual review of genetics · 2024Review
- Genetic and developmental divergence in the neural crest programme between cichlid fish species.bioRxiv : the preprint server for biology · 2024Article
- Neural crest cells as a source of microevolutionary variation.Seminars in cell & developmental biology · 2023Review
- Fgf8 dosage regulates jaw shape and symmetry through pharyngeal-cardiac tissue relationships.Developmental dynamics : an official publication of the American Association of Anatomists · 2022Article
- Article
- Article
- Early shape divergence of developmental trajectories in the jaw of galeomorph sharks.Frontiers in zoology · 2022Article
- Scaling of internal organs during Drosophila embryonic development.Biophysical journal · 2021Article
- Taste buds are not derived from neural crest in mouse, chicken, and zebrafish.Developmental biology · 2021Article
- Making and shaping endochondral and intramembranous bones.Developmental dynamics : an official publication of the American Association of Anatomists · 2021Review
- Exceptional Changes in Skeletal Anatomy under Domestication: The Case of Brachycephaly.Integrative organismal biology (Oxford, England) · 2021Article
- Stable integration of an optimized inducible promoter system enables spatiotemporal control of gene expression throughout avian development.Biology open · 2020Article
- Hair follicle stem cells differentiation into bone cells on collagen scaffold.Cell and tissue banking · 2020Article
- Differences in Cell Proliferation and Craniofacial Phenotype of Closely Related Species in the Pupfish Genus Cyprinodon.The Journal of heredity · 2020Article
- Disconnect between the developing eye and craniofacial prominences in the avian embryo.Mechanisms of development · 2020Article
- Molecular and cellular mechanisms underlying the evolution of form and function in the amniote jaw.EvoDevo · 2019Review
- FGF and TGFβ signaling link form and function during jaw development and evolution.Developmental biology · 2018Article
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Authors and funding
4 authors.
Funding
Abstract
Variation in jaw size during evolution has been crucial for the adaptive radiation of vertebrates, yet variation in jaw size during development is often associated with disease. To test the hypothesis that early developmental events regulating neural crest (NC) progenitors contribute to species-specific differences in size, we investigated mechanisms through which two avian species, duck and quail, achieve their remarkably different jaw size. At early stages, duck exhibit an anterior shift in brain regionalization yielding a shorter, broader, midbrain. We find no significant difference in the total number of pre-migratory NC; however, duck concentrate their pre-migratory NC in the midbrain, which contributes to an increase in size of the post-migratory NC population allocated to the mandibular arch. Subsequent differences in proliferation lead to a progressive increase in size of the duck mandibular arch relative to that of quail. To test the role of pre-migratory NC progenitor number in regulating jaw size, we reduced and augmented NC progenitors. In contrast to previous reports of regeneration by NC precursors, we find that neural fold extirpation results in a loss of NC precursors. Despite this reduction in their numbers, post-migratory NC progenitors compensate, producing a symmetric and normal-sized jaw. Our results suggest that evolutionary modification of multiple aspects of NC cell biology, including NC allocation within the jaw primordia and NC-mediated proliferation, have been important to the evolution of jaw size. Furthermore, our finding of NC post-migratory compensatory mechanisms potentially extends the developmental time frame for treatments of disease or injury associated with NC progenitor loss.
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